4-Hydroxynonenal Induces G2/M Phase Cell Cycle Arrest by Activation of the Ataxia Telangiectasia Mutated and Rad3-related Protein (ATR)/Checkpoint Kinase 1 (Chk1) Signaling Pathway

The expression and function of vascular endothelial growth factor in retinal pigment epithelial (RPE) cells is regulated by 4-hydroxynonenal (HNE) and glutathione S-transferaseA4-4

(2011) Rit Vatsyayan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Checkpoint control and cancer

(2011) R H Medema et al.   ONCOGENE

Mechanisms of 4-Hydroxy-2-nonenal Induced Pro- and Anti-Apoptotic Signaling

(2010) Pankaj Chaudhary et al.   BIOCHEMISTRY

Role of 4-hydroxynonenal in epidermal growth factor receptor-mediated signaling in retinal pigment epithelial cells

(2010) Rit Vatsyayan et al.   EXPERIMENTAL EYE RESEARCH

Cdc25 Phosphatases Are Required for Timely Assembly of CDK1-Cyclin B at the G2/M Transition

(2010) Oleg Timofeev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence That Gsta4 Modifies Susceptibility to Skin Tumor Development in Mice and Humans

(2010) Erika L. Abel et al.   JNCI-Journal of the National Cancer Institute

A minority of foci or pan-nuclear apoptotic staining of  H2AX in the S phase after UV damage contain DNA double-strand breaks

(2010) S. de Feraudy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disruption of the mGsta4 Gene Increases Life Span of C57BL Mice

(2009) S. P. Singh et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

4-Hydroxynonenal induces p53-mediated apoptosis in retinal pigment epithelial cells

(2008) Abha Sharma et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Self-regulatory role of 4-hydroxynonenal in signaling for stress-induced programmed cell death

(2008) Yogesh C. Awasthi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Regulation of DNA repair throughout the cell cycle

(2008) Dana Branzei et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

4-Hydroxynonenal: A membrane lipid oxidation product of medicinal interest

(2007) G. Poli et al.   MEDICINAL RESEARCH REVIEWS