Leucine Facilitates Insulin Signaling through a GαiProtein-dependent Signaling Pathway in Hepatocytes

Hyperinsulinemia Drives Diet-Induced Obesity Independently of Brain Insulin Production

(2012) Arya E. Mehran et al.   Cell Metabolism

Excess Exposure to Insulin Is the Primary Cause of Insulin Resistance and its Associated Atherosclerosis

(2011) Wenhong Cao et al.   Current Molecular Pharmacology

β-Arrestins: multifunctional signaling adaptors in type 2 diabetes

(2010) Xiaotao Feng et al.   MOLECULAR BIOLOGY REPORTS

Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress

(2010) Shomit Sengupta et al.   MOLECULAR CELL

Chronic leucine supplementation improves glycemic control in etiologically distinct mouse models of obesity and diabetes mellitus

(2010) Kaiying Guo et al.   Nutrition & Metabolism

Leucine metabolism in regulation of insulin secretion from pancreatic beta cells

(2010) Jichun Yang et al.   NUTRITION REVIEWS

A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance

(2009) Christopher B. Newgard et al.   Cell Metabolism

Hepatic Autophagy Is Suppressed in the Presence of Insulin Resistance and Hyperinsulinemia

(2009) Hui-Yu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin Is a Stronger Inducer of Insulin Resistance than Hyperglycemia in Mice with Type 1 Diabetes Mellitus (T1DM)

(2009) Hui-Yu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prolonged Exposure to Insulin Suppresses Mitochondrial Production in Primary Hepatocytes

(2009) Hui-Yu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Augmentation of insulin secretion by leucine supplementation in malnourished rats: possible involvement of the phosphatidylinositol 3-phosphate kinase/mammalian target protein of rapamycin pathway

(2009) Eliane Filiputti et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Amino acid regulation of TOR complex 1

(2008) Joseph Avruch et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Insulin Resistance and Hyperinsulinemia: Is hyperinsulinemia the cart or the horse?

(2008) M. H. Shanik et al.   DIABETES CARE

Inhibition of Gluconeogenesis in Primary Hepatocytes by Stromal Cell-derived Factor-1 (SDF-1) through a c-Src/Akt-dependent Signaling Pathway

(2008) Hui-Yu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Suppression of Hepatic Glucose Production by Human Neutrophil α-Defensins through a Signaling Pathway Distinct from Insulin

(2008) Hui-Yu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY