trans-(−)-ϵ-Viniferin Increases Mitochondrial Sirtuin 3 (SIRT3), Activates AMP-activated Protein Kinase (AMPK), and Protects Cells in Models of Huntington Disease

Neuroprotective properties of resveratrol and derivatives

(2011) Tristan Richard et al.   Annals of the New York Academy of Sciences

Energy deficit in Huntington disease: why it matters

(2011) Fanny Mochel et al.   JOURNAL OF CLINICAL INVESTIGATION

The SirT3 Divining Rod Points to Oxidative Stress

(2011) Eric L. Bell et al.   MOLECULAR CELL

Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity

(2011) Wenjun Song et al.   NATURE MEDICINE

SirT3 suppresses hypoxia inducible factor 1α and tumor growth by inhibiting mitochondrial ROS production

(2011) E L Bell et al.   ONCOGENE

Neuronal Sirt3 Protects against Excitotoxic Injury in Mouse Cortical Neuron Culture

(2011) Sun Hee Kim et al.   PLoS One

What Is New for an Old Molecule? Systematic Review and Recommendations on the Use of Resveratrol

(2011) Ole Vang et al.   PLoS One

Evidence of Oxidant Damage in Huntington's Disease: Translational Strategies Using Antioxidants

(2010) Edward C. Stack et al.   Annals of the New York Academy of Sciences

Resveratrol protects against peripheral deficits in a mouse model of Huntington's disease

(2010) Daniel J. Ho et al.   EXPERIMENTAL NEUROLOGY

ERK activation by the polyphenols fisetin and resveratrol provides neuroprotection in multiple models of Huntington's disease

(2010) Pamela Maher et al.   HUMAN MOLECULAR GENETICS

The interrelationship between mitochondrial dysfunction and transcriptional dysregulation in Huntington disease

(2010) Youngnam N. Jin et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Characterization of murine SIRT3 transcript variants and corresponding protein products

(2010) Yongjie Yang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Bringing natural products into the fold – exploring the therapeutic lead potential of secondary metabolites for the treatment of protein-misfolding-related neurodegenerative diseases

(2010) P. Matthew Joyner et al.   NATURAL PRODUCT REPORTS

Biochemical characterization, localization, and tissue distribution of the longer form of mouse SIRT3

(2010) Lei Jin et al.   PROTEIN SCIENCE

Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling

(2010) Eric Verdin et al.   TRENDS IN BIOCHEMICAL SCIENCES

Regulation of Succinate Dehydrogenase Activity by SIRT3 in Mammalian Mitochondria

(2009) Huseyin Cimen et al.   BIOCHEMISTRY

Cause and consequence: Mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative diseases

(2009) Gary E. Gibson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

NAD+-dependent Deacetylase SIRT3 Regulates Mitochondrial Protein Synthesis by Deacetylation of the Ribosomal Protein MRPL10

(2009) Yongjie Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exogenous NAD Blocks Cardiac Hypertrophic Response via Activation of the SIRT3-LKB1-AMP-activated Kinase Pathway

(2009) Vinodkumar B. Pillai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington’s disease

(2008) Judit Pallos et al.   HUMAN MOLECULAR GENETICS

A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

(2008) B.-H. Ahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA