A Mutation inTNNC1-encoded Cardiac Troponin C, TNNC1-A31S, Predisposes to Hypertrophic Cardiomyopathy and Ventricular Fibrillation

Novel frameshift mutation in Troponin C ( TNNC1) associated with hypertrophic cardiomyopathy and sudden death

(2011) Wendy K. Chung et al.   CARDIOLOGY IN THE YOUNG

Junctophilin-2 Expression Silencing Causes Cardiocyte Hypertrophy and Abnormal Intracellular Calcium-Handling

(2011) Andrew P. Landstrom et al.   Circulation-Heart Failure

Mapping copy number variation by population-scale genome sequencing

(2011) Ryan E. Mills et al.   NATURE

Mutation Type Is Not Clinically Useful in Predicting Prognosis in Hypertrophic Cardiomyopathy

(2010) Andrew P. Landstrom et al.   CIRCULATION

Predicting Cardiomyopathic Phenotypes by Altering Ca2+Affinity of Cardiac Troponin C

(2010) Michelle S. Parvatiyar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Strong Cross-bridges Potentiate the Ca2+Affinity Changes Produced by Hypertrophic Cardiomyopathy Cardiac Troponin C Mutants in Myofilaments

(2010) Jose Renato Pinto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcium binding kinetics of troponin C strongly modulate cooperative activation and tension kinetics in cardiac muscle

(2010) Kareen L. Kreutziger et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The cardiac troponin C mutation Leu29Gln found in a patient with hypertrophic cardiomyopathy does not alter contractile parameters in skinned murine myocardium

(2009) Axel Neulen et al.   BASIC RESEARCH IN CARDIOLOGY

A Functional and Structural Study of Troponin C Mutations Related to Hypertrophic Cardiomyopathy

(2009) Jose Renato Pinto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutations in Troponin that cause HCM, DCM AND RCM: What can we learn about thin filament function?

(2009) Ruth H. Willott et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Diagnostic, Prognostic, and Therapeutic Implications of Genetic Testing for Hypertrophic Cardiomyopathy

(2009) J. Martijn Bos et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Functional Consequences of the Human Cardiac Troponin I Hypertrophic Cardiomyopathy Mutation R145G in Transgenic Mice

(2008) Yuhui Wen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Challenging Current Paradigms Related to Cardiomyopathies

(2008) David Dweck et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular and functional characterization of novel hypertrophic cardiomyopathy susceptibility mutations in TNNC1-encoded troponin C

(2008) Andrew P. Landstrom et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Modulation of troponin C affinity for the thin filament by different cross-bridge states in skinned skeletal muscle fibers

(2008) José Renato Pinto et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Familial hypertrophic cardiomyopathy-related cardiac troponin C mutation L29Q affects Ca2+ binding and myofilament contractility

(2008) Bo Liang et al.   PHYSIOLOGICAL GENOMICS