A Dual Role for Receptor-interacting Protein Kinase 2 (RIP2) Kinase Activity in Nucleotide-binding Oligomerization Domain 2 (NOD2)-dependent Autophagy

The Nucleotide Synthesis Enzyme CAD Inhibits NOD2 Antibacterial Function in Human Intestinal Epithelial Cells

(2012) Amy L. Richmond et al.   GASTROENTEROLOGY

Autophagy regulates ROS-induced cellular senescence via p21 in a p38 MAPKα dependent manner

(2011) Yi Luo et al.   EXPERIMENTAL GERONTOLOGY

Digesting the genetics of inflammatory bowel disease: Insights from studies of autophagy risk genes

(2011) Amrita Kabi et al.   INFLAMMATORY BOWEL DISEASES

TLR2 and RIP2 Pathways Mediate Autophagy ofListeria monocytogenesvia Extracellular Signal-regulated Kinase (ERK) Activation

(2011) Paras K. Anand et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NOD2, an intracellular innate immune sensor involved in host defense and Crohn's disease

(2011) W Strober et al.   Mucosal Immunology

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

Loss of PINK1 function decreases PP2A activity and promotes autophagy in dopaminergic cells and a murine model

(2011) Zhifeng Qi et al.   NEUROCHEMISTRY INTERNATIONAL

NOD2 controls the nature of the inflammatory response and subsequent fate of Mycobacterium tuberculosis and M. bovis BCG in human macrophages

(2010) Michelle N. Brooks et al.   CELLULAR MICROBIOLOGY

Dephosphorylation of Carma1 by PP2A negatively regulates T-cell activation

(2010) Andrea C Eitelhuber et al.   EMBO JOURNAL

ATG16L1 and NOD2 Interact in an Autophagy-Dependent Antibacterial Pathway Implicated in Crohn's Disease Pathogenesis

(2010) Craig R. Homer et al.   GASTROENTEROLOGY

Inhibition of RIP2's tyrosine kinase activity limits NOD2-driven cytokine responses

(2010) J. T. Tigno-Aranjuez et al.   GENES & DEVELOPMENT

Endotoxin Conditioning Induces VCP/p97-mediated and Inducible Nitric-oxide Synthase-dependent Tyr284Nitration in Protein Phosphatase 2A

(2010) Takashi Ohama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

Tap42-associated protein phosphatase type 2A negatively regulates induction of autophagy

(2009) Tomohiro Yorimitsu et al.   Autophagy

Coordinated regulation of autophagy by p38α MAPK through mAtg9 and p38IP

(2009) Jemma L Webber et al.   EMBO JOURNAL

The Kinase Activity of Rip2 Determines Its Stability and Consequently Nod1- and Nod2-mediated Immune Responses

(2009) Chiara Nembrini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Role for p38 Stress-Activated Protein Kinase in Regulation of Cell Growth via TORC1

(2009) M. Cully et al.   MOLECULAR AND CELLULAR BIOLOGY

From Promiscuity to Precision: Protein Phosphatases Get a Makeover

(2009) David M. Virshup et al.   MOLECULAR CELL

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

(2009) Leonardo H Travassos et al.   NATURE IMMUNOLOGY

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

(2009) Rachel Cooney et al.   NATURE MEDICINE

LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection

(2008) Hua Yuan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Effect of Rifampicin to Inhibit Rapamycin-Induced Autophagy via the Suppression of Protein Phosphatase 2A Activity

(2008) In-Hoo Park et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

PP2A holoenzyme assembly: in cauda venenum (the sting is in the tail)

(2008) Veerle Janssens et al.   TRENDS IN BIOCHEMICAL SCIENCES

Multiple pathways regulated by the tumor suppressor PP2A in transformation

(2008) Jukka Westermarck et al.   TRENDS IN MOLECULAR MEDICINE