Contradictory Functions (Activation/Termination) of Neutrophil Proteinase 3 Enzyme (PR3) in Interleukin-33 Biological Activity

An IL-1 Cytokine Member, IL-33, Induces Human Basophil Activation via Its ST2 Receptor

(2014) M. Suzukawa et al.   JOURNAL OF IMMUNOLOGY

Identification of Constitutively Active Interleukin 33 (IL-33) Splice Variant

(2011) Jaewoo Hong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy

(2010) W. A. Verri et al.   ANNALS OF THE RHEUMATIC DISEASES

Generation of Anti-Proteinase 3 Monoclonal Antibodies and Development of Immunological Methods to Detect Endogenous Proteinase 3

(2010) Suyoung Bae et al.   HYBRIDOMA

Mature interleukin-33 is produced by calpain-mediated cleavage in vivo

(2009) Morisada Hayakawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

IL-33 Raises Alarm

(2009) Mohamed Lamkanfi et al.   IMMUNITY

Suppression of Interleukin-33 Bioactivity through Proteolysis by Apoptotic Caspases

(2009) Alexander U. Lüthi et al.   IMMUNITY

Basophils: A Nonredundant Contributor to Host Immunity

(2009) Brandon M. Sullivan et al.   IMMUNITY

IL-33–activated dendritic cells induce an atypical TH2-type response

(2009) Matthew A. Rank et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IL-33 Amplifies the Polarization of Alternatively Activated Macrophages That Contribute to Airway Inflammation

(2009) M. Kurowska-Stolarska et al.   JOURNAL OF IMMUNOLOGY

Caspase-1, Caspase-8, and Calpain Are Dispensable for IL-33 Release by Macrophages

(2009) T. Ohno et al.   JOURNAL OF IMMUNOLOGY

The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1

(2009) C. Cayrol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells

(2009) L. Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design of selective substrates of proteinase 3 using combinatorial chemistry methods

(2008) Magdalena Wysocka et al.   ANALYTICAL BIOCHEMISTRY

Human basophils and eosinophils are the direct target leukocytes of the novel IL-1 family member IL-33

(2008) T. Pecaric-Petkovic et al.   BLOOD

The IL-1 receptor accessory protein (AcP) is required for IL-33 signaling and soluble AcP enhances the ability of soluble ST2 to inhibit IL-33

(2008) Gaby Palmer et al.   CYTOKINE

IL-1, IL-18, and IL-33 families of cytokines

(2008) William P. Arend et al.   IMMUNOLOGICAL REVIEWS

Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system

(2008) Y. Kondo et al.   INTERNATIONAL IMMUNOLOGY

IL-33 amplifies both Th1- and Th2-type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK Cells

(2008) M. D. Smithgall et al.   INTERNATIONAL IMMUNOLOGY

A novel IL-1 family cytokine, IL-33, potently activates human eosinophils

(2008) W. Brett Cherry et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

CD34+ hemopoietic progenitor cells are potent effectors of allergic inflammation

(2008) Zoulfia Allakhverdi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Interleukin-33 enhances adhesion, CD11b expression and survival in human eosinophils

(2008) Maho Suzukawa et al.   LABORATORY INVESTIGATION

The IL-1-Like Cytokine IL-33 Is Constitutively Expressed in the Nucleus of Endothelial Cells and Epithelial Cells In Vivo: A Novel ‘Alarmin’?

(2008) Christine Moussion et al.   PLoS One