Sulforaphane Induction of p21Cip1Cyclin-dependent Kinase Inhibitor Expression Requires p53 and Sp1 Transcription Factors and Is p53-dependent

Sulforaphane induces apoptosis in human hepatic cancer cells through inhibition of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase4, mediated by hypoxia inducible factor-1-dependent pathway

(2011) Young Keul Jeon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Induction of apoptosis by sulforaphane in highly metastatic B16F-10 melanoma cells

(2011) Thayele Purayil Hamsa et al.   DRUG AND CHEMICAL TOXICOLOGY

Protein Kinase C (PKC) δ Suppresses Keratinocyte Proliferation by Increasing p21Cip1Level by a KLF4 Transcription Factor-dependent Mechanism

(2011) Yap Ching Chew et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

D,L-sulforaphane-induced apoptosis in human breast cancer cells is regulated by the adapter protein p66Shc

(2011) Kozue Sakao et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Differential effects of sulforaphane on histone deacetylases, cell cycle arrest and apoptosis in normal prostate cells versus hyperplastic and cancerous prostate cells

(2011) John D. Clarke et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The impact of acetylation and deacetylation on the p53 pathway

(2011) Christopher L. Brooks et al.   Protein & Cell

p300 Alters Keratinocyte Cell Growth and Differentiation through Regulation of p21Waf1/CIP1

(2010) Ping-Pui Wong et al.   PLoS One

Sulforaphane Causes Epigenetic Repression of hTERT Expression in Human Breast Cancer Cell Lines

(2010) Syed M. Meeran et al.   PLoS One

Sulforaphane but not ascorbigen, indole-3-carbinole and ascorbic acid activates the transcription factor Nrf2 and induces phase-2 and antioxidant enzymes in human keratinocytes in culture

(2009) Anika E. Wagner et al.   EXPERIMENTAL DERMATOLOGY

Dietary Sulforaphane, a Histone Deacetylase Inhibitor for Cancer Prevention

(2009) Emily Ho et al.   JOURNAL OF NUTRITION

Sulforaphane suppresses ultraviolet B-induced inflammation in HaCaT keratinocytes and HR-1 hairless mice☆☆☆

(2009) Akira Shibata et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Targeting NRF2 signaling for cancer chemoprevention

(2009) Mi-Kyoung Kwak et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Genistein Induces the p21WAF1/CIP1 and p16INK4a Tumor Suppressor Genes in Prostate Cancer Cells by Epigenetic Mechanisms Involving Active Chromatin Modification

(2008) S. Majid et al.   CANCER RESEARCH

p21 and p27: roles in carcinogenesis and drug resistance

(2008) Abde M. Abukhdeir et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

The OGF–OGFr Axis Utilizes the p16INK4a and p21WAF1/CIP1 Pathways to Restrict Normal Cell Proliferation

(2008) Fan Cheng et al.   MOLECULAR BIOLOGY OF THE CELL

Temporal changes in gene expression induced by sulforaphane in human prostate cancer cells

(2008) Suvarna Bhamre et al.   PROSTATE