Human Mitochondrial DNA Helicase TWINKLE Is Both an Unwinding and Annealing Helicase

The mitochondrial DNA helicase TWINKLE can assemble on a closed circular template and support initiation of DNA synthesis

(2011) Elisabeth Jemt et al.   NUCLEIC ACIDS RESEARCH

Single-Stranded DNA Binding Proteins Unwind the Newly Synthesized Double-Stranded DNA of Model Miniforks

(2010) Emmanuelle Delagoutte et al.   BIOCHEMISTRY

The human mitochondrial replication fork in health and disease

(2010) Sjoerd Wanrooij et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Disease Variants of the Human Mitochondrial DNA Helicase Encoded byC10orf2Differentially Alter Protein Stability, Nucleotide Hydrolysis, and Helicase Activity

(2010) Matthew J. Longley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic Effects of Cofactors and DNA on the Oligomeric State of Human Mitochondrial DNA Helicase

(2010) Tawn D. Ziebarth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Roles of the N- and C-Terminal Regions of the Human Mitochondrial Single-Stranded DNA-Binding Protein

(2010) Marcos T. Oliveira et al.   PLoS One

Eukaryotic DNA replication control: Lock and load, then fire

(2009) Dirk Remus et al.   CURRENT OPINION IN CELL BIOLOGY

Dual DNA unwinding activities of the Rothmund–Thomson syndrome protein, RECQ4

(2009) Xiaohua Xu et al.   EMBO JOURNAL

Human Heart Mitochondrial DNA Is Organized in Complex Catenated Networks Containing Abundant Four-way Junctions and Replication Forks

(2009) Jaakko L. O. Pohjoismäki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure–function defects of the twinkle amino-terminal region in progressive external ophthalmoplegia

(2008) Teresa Holmlund et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Branch migration enzyme as a Brownian ratchet

(2008) Ivan Rasnik et al.   EMBO JOURNAL

Twinkle mutations associated with autosomal dominant progressive external ophthalmoplegia lead to impaired helicase function and in vivo mtDNA replication stalling

(2008) Steffi Goffart et al.   HUMAN MOLECULAR GENETICS

Physiological and Biochemical Defects in Carboxyl-terminal Mutants of Mitochondrial DNA Helicase

(2008) Yuichi Matsushima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure–Function Defects of the TWINKLE Linker Region in Progressive External Ophthalmoplegia

(2008) Jenny A. Korhonen et al.   JOURNAL OF MOLECULAR BIOLOGY