Role of p70S6K1-mediated Phosphorylation of eIF4B and PDCD4 Proteins in the Regulation of Protein Synthesis

Stable isotope-labelling analysis of the impact of inhibition of the mammalian target of rapamycin on protein synthesis

(2012) Yilin Huo et al.   BIOCHEMICAL JOURNAL

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

A unifying model for mTORC1-mediated regulation of mRNA translation

(2012) Carson C. Thoreen et al.   NATURE

ERK and Akt signaling pathways function through parallel mechanisms to promote mTORC1 signaling

(2011) Jeremiah N. Winter et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Simvastatin represses protein synthesis in the muscle-derived C2C12 cell line with a concomitant reduction in eukaryotic initiation factor 2B expression

(2011) Alexander P. Tuckow et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Duplex Unwinding and ATPase Activities of the DEAD-Box Helicase eIF4A Are Coupled by eIF4G and eIF4B

(2011) Ali R. ze et al.   JOURNAL OF MOLECULAR BIOLOGY

Insulin like growth factor-1-induced phosphorylation and altered distribution of tuberous sclerosis complex (TSC)1/TSC2 in C2C12 myotubes

(2010) Mitsunori Miyazaki et al.   FEBS Journal

ERK1/2 Phosphorylate Raptor to Promote Ras-dependent Activation of mTOR Complex 1 (mTORC1)

(2010) Audrey Carriere et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synergistic activation of eIF4A by eIF4B and eIF4G

(2010) Klaus H. Nielsen et al.   NUCLEIC ACIDS RESEARCH

Identification of FUSE-binding protein 1 as a regulatory mRNA-binding protein that represses nucleophosmin translation

(2010) M E Olanich et al.   ONCOGENE

An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1

(2009) Carson C. Thoreen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of the eIF4A-PDCD4 complex

(2009) J. H. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blocking eukaryotic initiation factor 4F complex formation does not inhibit the mTORC1-dependent activation of protein synthesis in cardiomyocytes

(2008) Brandon P. H. Huang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains

(2008) C. Suzuki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA