MicroRNA-30d Induces Insulin Transcription Factor MafA and Insulin Production by Targeting Mitogen-activated Protein 4 Kinase 4 (MAP4K4) in Pancreatic β-Cells

miRNAs control insulin content in pancreatic β-cells via downregulation of transcriptional repressors

(2011) Tal Melkman-Zehavi et al.   EMBO JOURNAL

Sirt1 and mir-9 expression is regulated during glucose-stimulated insulin secretion in pancreatic β-islets

(2011) Deepti Ramachandran et al.   FEBS Journal

miR-29a and miR-29b Contribute to Pancreatic  -Cell-Specific Silencing of Monocarboxylate Transporter 1 (Mct1)

(2011) T. J. Pullen et al.   MOLECULAR AND CELLULAR BIOLOGY

Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism

(2011) Sabine D. Jordan et al.   NATURE CELL BIOLOGY

Diabetes mellitus, a microRNA-related disease?

(2011) Claudiane Guay et al.   Translational Research

MafA and MafB activity in pancreatic β cells

(2011) Yan Hang et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Elimination of Negative Feedback Control Mechanisms Along the Insulin Signaling Pathway Improves  -Cell Function Under Stress

(2010) D. Gurevitch et al.   DIABETES

Regulation of MafA Expression in Pancreatic  -Cells in db/db Mice With Diabetes

(2010) T.-a. Matsuoka et al.   DIABETES

Involvement of MicroRNAs in the Cytotoxic Effects Exerted by Proinflammatory Cytokines on Pancreatic  -Cells

(2010) E. Roggli et al.   DIABETES

Phosphorylation within the MafA N Terminus Regulates C-terminal Dimerization and DNA Binding

(2010) Shuangli Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcineurin/Nuclear Factor of Activated T Cells and MAPK Signaling Induce TNF-α Gene Expression in Pancreatic Islet Endocrine Cells

(2010) Michael C. Lawrence et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-125a is over-expressed in insulin target tissues in a spontaneous rat model of Type 2 Diabetes

(2009) Blanca M Herrera et al.   BMC Medical Genomics

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Silencing Mitogen-activated Protein 4 Kinase 4 (MAP4K4) Protects Beta Cells from Tumor Necrosis Factor-α-induced Decrease of IRS-2 and Inhibition of Glucose-stimulated Insulin Secretion

(2009) Karim Bouzakri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Map4k4Negatively Regulates Peroxisome Proliferator-activated Receptor (PPAR) γ Protein Translation by Suppressing the Mammalian Target of Rapamycin (mTOR) Signaling Pathway in Cultured Adipocytes

(2009) Kalyani V. P. Guntur et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-375 maintains normal pancreatic  - and  -cell mass

(2009) M. N. Poy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic mechanisms in the development of type 2 diabetes

(2009) Sara E. Pinney et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Multiple kinases regulate mafA expression in the pancreatic beta cell line MIN6

(2008) Nathan L. Vanderford et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Glucose regulation of insulin gene expression in pancreatic β-cells

(2008) Sreenath S. Andrali et al.   BIOCHEMICAL JOURNAL

Role of microRNAs in diabetes

(2008) X TANG et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

miR-375 Targets 3'-Phosphoinositide-Dependent Protein Kinase-1 and Regulates Glucose-Induced Biological Responses in Pancreatic  -Cells

(2008) A. El Ouaamari et al.   DIABETES

Pdx1 and BETA2/NeuroD1 Participate in a Transcriptional Complex That Mediates Short-range DNA Looping at the Insulin Gene

(2008) Daniella A. Babu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Expression of MicroRNA miR-107 Decreases Early in Alzheimer's Disease and May Accelerate Disease Progression through Regulation of  -Site Amyloid Precursor Protein-Cleaving Enzyme 1

(2008) W.-X. Wang et al.   JOURNAL OF NEUROSCIENCE

Identification of glucose-regulated miRNAs from pancreatic   cells reveals a role for miR-30d in insulin transcription

(2008) X. Tang et al.   RNA