ATF4-dependent Regulation of the JMJD3 Gene during Amino Acid Deprivation Can Be Rescued in Atf4-deficient Cells by Inhibition of Deacetylation

The Transcription Factor Network Associated With the Amino Acid Response in Mammalian Cells

(2012) Michael S. Kilberg et al.   Advances in Nutrition

The chromatin-binding protein HMGN3 stimulates histone acetylation and transcription across theGlyt1gene

(2011) Gráinne Barkess et al.   BIOCHEMICAL JOURNAL

Maternal protein restriction during pregnancy induces CCAAT/enhancer-binding protein (C/EBPβ) expression through the regulation of histone modification at its promoter region in female offspring rat skeletal muscle

(2011) Shasha Zheng et al.   Epigenetics

Epigenetic switch involved in activation of pioneer factor FOXA1-dependent enhancers

(2011) A. A. Serandour et al.   GENOME RESEARCH

Auto-activation of c-JUNGene by Amino Acid Deprivation of Hepatocellular Carcinoma Cells Reveals a Novel c-JUN-mediated Signaling Pathway

(2011) Lingchen Fu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein restriction during gestation alters histone modifications at the glucose transporter 4 (GLUT4) promoter region and induces GLUT4 expression in skeletal muscle of female rat offspring

(2011) Shasha Zheng et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Jmjd3 and UTX Play a Demethylase-Independent Role in Chromatin Remodeling to Regulate T-Box Family Member-Dependent Gene Expression

(2010) Sara A. Miller et al.   MOLECULAR CELL

Widespread transcription at neuronal activity-regulated enhancers

(2010) Tae-Kyung Kim et al.   NATURE

The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection

(2010) Takashi Satoh et al.   NATURE IMMUNOLOGY

Expression profiling after activation of amino acid deprivation response in HepG2 human hepatoma cells

(2010) Jixiu Shan et al.   PHYSIOLOGICAL GENOMICS

Amino Acid Availability Controls TRB3 Transcription in Liver through the GCN2/eIF2α/ATF4 Pathway

(2010) Valérie Carraro et al.   PLoS One

Epigenetic regulation of the alternatively activated macrophage phenotype

(2009) M. Ishii et al.   BLOOD

Genome-wide Mapping of HATs and HDACs Reveals Distinct Functions in Active and Inactive Genes

(2009) Zhibin Wang et al.   CELL

Jmjd3 contributes to the control of gene expression in LPS-activated macrophages

(2009) Francesca De Santa et al.   EMBO JOURNAL

Epigenetic reprogramming during wound healing: loss of polycomb-mediated silencing may enable upregulation of repair genes

(2009) Tanya Shaw et al.   EMBO REPORTS

Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS

(2009) M. Barradas et al.   GENES & DEVELOPMENT

The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence

(2009) K. Agger et al.   GENES & DEVELOPMENT

Protein or amino acid deprivation differentially regulates the hepatic forkhead box protein A (FOXA) genes through an activating transcription factor-4-independent pathway

(2009) Nan Su et al.   HEPATOLOGY

GCN2 Protein Kinase Is Required to Activate Amino Acid Deprivation Responses in Mice Treated with the Anti-cancer Agent l-Asparaginase

(2009) Piyawan Bunpo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a Novel Amino Acid Response Pathway Triggering ATF2 Phosphorylation in Mammals

(2009) C. Chaveroux et al.   MOLECULAR AND CELLULAR BIOLOGY

ATF4-dependent transcription mediates signaling of amino acid limitation

(2009) Michael S. Kilberg et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Deprivation of protein or amino acid induces C/EBPβ synthesis and binding to amino acid response elements, but its action is not an absolute requirement for enhanced transcription

(2008) Michelle M. Thiaville et al.   BIOCHEMICAL JOURNAL

Amino acid limitation regulates the expression of genes involved in several specific biological processes through GCN2-dependent and GCN2-independent pathways

(2008) Christiane Deval et al.   FEBS Journal

MEK Signaling Is Required for Phosphorylation of eIF2α following Amino Acid Limitation of HepG2 Human Hepatoma Cells

(2008) Michelle M. Thiaville et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Despite Increased ATF4 Binding at the C/EBP-ATF Composite Site following Activation of the Unfolded Protein Response, System A Transporter 2 (SNAT2) Transcription Activity Is Repressed in HepG2 Cells

(2008) Altin Gjymishka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

C/EBP Homology Protein (CHOP) Interacts with Activating Transcription Factor 4 (ATF4) and Negatively Regulates the Stress-dependent Induction of the Asparagine Synthetase Gene

(2008) Nan Su et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

C/EBP  Induces Chromatin Opening at a Cell-Type-Specific Enhancer

(2008) A. Plachetka et al.   MOLECULAR AND CELLULAR BIOLOGY

HepG2/C3A cells respond to cysteine deprivation by induction of the amino acid deprivation/integrated stress response pathway

(2008) Jeong-In Lee et al.   PHYSIOLOGICAL GENOMICS

The Histone H3 Lysine 27-Specific Demethylase Jmjd3 Is Required for Neural Commitment

(2008) Thomas Burgold et al.   PLoS One