NOX5 in Human Spermatozoa

Insights into the biochemistry of the ubiquitous NhaP family of cation/H+ antiportersThis paper is one of a selection of papers published in a Special Issue entitled CSBMCB 53rd Annual Meeting — Membrane Proteins in Health and Disease, and has undergone the Journal’s usual peer review process.

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Progesterone activates the principal Ca2+ channel of human sperm

(2011) Polina V. Lishko et al.   NATURE

Bile Acid Reflux Contributes to Development of Esophageal Adenocarcinoma via Activation of Phosphatidylinositol-Specific Phospholipase C 2 and NADPH Oxidase NOX5-S

(2010) J. Hong et al.   CANCER RESEARCH

Shedding Light on Sperm pHertility

(2010) Harvey M. Florman et al.   CELL

Acid Extrusion from Human Spermatozoa Is Mediated by Flagellar Voltage-Gated Proton Channel

(2010) Polina V. Lishko et al.   CELL

First in Class, Potent, and Orally Bioavailable NADPH Oxidase Isoform 4 (Nox4) Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis

(2010) Benoı̂t Laleu et al.   JOURNAL OF MEDICINAL CHEMISTRY

The role of Hv1 and CatSper channels in sperm activation

(2010) Polina V. Lishko et al.   JOURNAL OF PHYSIOLOGY-LONDON

HVCN1 modulates BCR signal strength via regulation of BCR-dependent generation of reactive oxygen species

(2010) Melania Capasso et al.   NATURE IMMUNOLOGY

A structural overview of the plasma membrane Na+,K+-ATPase and H+-ATPase ion pumps

(2010) J. Preben Morth et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Voltage-Gated Proton Channels Find Their Dream Job Managing the Respiratory Burst in Phagocytes

(2010) Thomas E. DeCoursey   PHYSIOLOGY

Molecular and Functional Characterization of Hv1 Proton Channel in Human Granulocytes

(2010) Gábor L. Petheő et al.   PLoS One

Evaluation of seminal zinc levels by atomic absorption in men with spinal cord injury

(2010) A P Alexandrino et al.   SPINAL CORD

Nox5 and the Regulation of Cellular Function

(2009) David J.R. Fulton   ANTIOXIDANTS & REDOX SIGNALING

Identification of Thr29as a Critical Phosphorylation Site That Activates the Human Proton ChannelHvcn1in Leukocytes

(2009) Boris Musset et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

VSOP/Hv1 proton channels sustain calcium entry, neutrophil migration, and superoxide production by limiting cell depolarization and acidification

(2009) Antoun El Chemaly et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Molecular Mechanism for Human Sperm Chemotaxis Mediated by Progesterone

(2009) Maria E. Teves et al.   PLoS One

Hv1 proton channels are required for high-level NADPH oxidase-dependent superoxide production during the phagocyte respiratory burst

(2009) I. S. Ramsey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Voltage-gated proton channels maintain pH in human neutrophils during phagocytosis

(2009) D. Morgan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nox5 mediates PDGF-induced proliferation in human aortic smooth muscle cells

(2008) Desmond B. Jay et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reactive oxygen-induced reactive oxygen formation during human sperm capacitation

(2008) Eve de Lamirande et al.   FREE RADICAL BIOLOGY AND MEDICINE

Sperm activation: Role of reactive oxygen species and kinases

(2007) Eve de Lamirande et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Novel redox-dependent regulation of NOX5 by the tyrosine kinase c-Abl

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