A Common Mechanism of Inhibition of theMycobacterium tuberculosisMycolic Acid Biosynthetic Pathway by Isoxyl and Thiacetazone

Mycobacterium tuberculosis Lacking All Mycolic Acid Cyclopropanation Is Viable but Highly Attenuated and Hyperinflammatory in Mice

(2012) Daniel Barkan et al.   INFECTION AND IMMUNITY

Mutations in the essential FAS II β-hydroxyacyl ACP dehydratase complex confer resistance to thiacetazone inMycobacterium tuberculosisandMycobacterium kansasii

(2012) Juan M. Belardinelli et al.   MOLECULAR MICROBIOLOGY

Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane

(2012) Anna E Grzegorzewicz et al.   Nature Chemical Biology

The structure–activity relationship of urea derivatives as anti-tuberculosis agents

(2011) Joshua R. Brown et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The Mycobacterium Tuberculosis FAS-II Dehydratases and Methyltransferases Define the Specificity of the Mycolic Acid Elongation Complexes

(2011) Sylvain Cantaloube et al.   PLoS One

Bioactivation of antituberculosis thioamide and thiourea prodrugs by bacterial and mammalian flavin monooxygenases

(2010) Clinton R. Nishida et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis

(2010) José A Caminero et al.   LANCET INFECTIOUS DISEASES

Mycolic acid methyltransferase, MmaA4, is necessary for thiacetazone susceptibility inMycobacterium tuberculosis

(2009) Anuradha Alahari et al.   MOLECULAR MICROBIOLOGY