Effective Killing of Leukemia Cells by the Natural Product OSW-1 through Disruption of Cellular Calcium Homeostasis

Synthesis of 5(6)-dihydro-OSW-1 analogs bearing three kinds of disaccharides linking at 15-hydroxy and their antitumor activities

(2011) Yuyao Guan et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of cholestane saponins as mimics of OSW-1 and their cytotoxic activities

(2011) Dan Zheng et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and Biological Activity of 22-Deoxo-23-oxa Analogues of Saponin OSW-1

(2011) Jadwiga Maj et al.   JOURNAL OF MEDICINAL CHEMISTRY

Natural products reveal cancer cell dependence on oxysterol-binding proteins

(2011) Anthony W G Burgett et al.   Nature Chemical Biology

Functional implications of sterol transport by the oxysterol-binding protein gene family

(2010) Mike H. Ngo et al.   BIOCHEMICAL JOURNAL

Synthesis of cholestane glycosides bearing OSW-1 disaccharide or its 1→4-linked analogue and their antitumor activities

(2010) Dan Zheng et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Dual inhibition of sodium-mediated proton and calcium efflux triggers non-apoptotic cell death in malignant gliomas

(2010) William Harley et al.   BRAIN RESEARCH

Lipid-regulated sterol transfer between closely apposed membranes by oxysterol-binding protein homologues

(2009) Timothy A. Schulz et al.   JOURNAL OF CELL BIOLOGY

Calcium Pumps in Health and Disease

(2009) Marisa Brini et al.   PHYSIOLOGICAL REVIEWS

Sodium-calcium exchanger complexed with GM1 ganglioside in nuclear membrane transfers calcium from nucleoplasm to endoplasmic reticulum

(2009) G. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effective killing of Gleevec-resistant CML cells with T315I mutation by a natural compound PEITC through redox-mediated mechanism

(2008) H Zhang et al.   LEUKEMIA

Role of sarco/endoplasmic reticulum calcium content and calcium ATPase activity in the control of cell growth and proliferation

(2008) Larissa Lipskaia et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY