Activation of Cannabinoid Receptor Type 1 (Cb1r) Disrupts Hepatic Insulin Receptor Signaling via Cyclic AMP-response Element-binding Protein H (Crebh)-mediated Induction ofLipin1Gene

Cannabinoid Receptor Type 1 (CB1R) Signaling Regulates Hepatic Gluconeogenesis via Induction of Endoplasmic Reticulum-bound Transcription Factor cAMP-responsive Element-binding Protein H (CREBH) in Primary Hepatocytes

(2011) Dipanjan Chanda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Estrogen-related Receptor γ (ERRγ) Is a Novel Transcriptional Regulator of Phosphatidic Acid Phosphatase, LIPIN1, and Inhibits Hepatic Insulin Signaling

(2011) Don-Kyu Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The transcription factor cyclic AMP–responsive element–binding protein H regulates triglyceride metabolism

(2011) Jung Hoon Lee et al.   NATURE MEDICINE

Regulation of Hepatic Gluconeogenesis by an ER-Bound Transcription Factor, CREBH

(2010) Min-Woo Lee et al.   Cell Metabolism

Lipid-induced insulin resistance: unravelling the mechanism

(2010) Varman T Samuel et al.   LANCET

Diacylglycerol-mediated insulin resistance

(2010) Derek M Erion et al.   NATURE MEDICINE

The liver-enriched transcription factor CREBH is nutritionally regulated and activated by fatty acids and PPARα

(2009) Hirosuke Danno et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Phosphatidate degradation: Phosphatidate phosphatases (lipins) and lipid phosphate phosphatases

(2009) David N. Brindley et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

TORC2 Regulates Hepatic Insulin Signaling via a Mammalian Phosphatidic Acid Phosphatase, LIPIN1

(2009) Dongryeol Ryu et al.   Cell Metabolism

The lipin family: mutations and metabolism

(2009) Karen Reue   CURRENT OPINION IN LIPIDOLOGY

Sterol-mediated Regulation of Human Lipin 1 Gene Expression in Hepatoblastoma Cells

(2009) Kenji Ishimoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ER Stress Controls Iron Metabolism Through Induction of Hepcidin

(2009) C. Vecchi et al.   SCIENCE

PKCε plays a causal role in acute ethanol-induced steatosis

(2008) J. Phillip Kaiser et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Paracrine Activation of Hepatic CB1 Receptors by Stellate Cell-Derived Endocannabinoids Mediates Alcoholic Fatty Liver

(2008) Won-il Jeong et al.   Cell Metabolism

Peripheral, but Not Central, CB1 Antagonism Provides Food Intake-Independent Metabolic Benefits in Diet-Induced Obese Rats

(2008) R. Nogueiras et al.   DIABETES

Hepatocyte nuclear factor 4α is implicated in endoplasmic reticulum stress-induced acute phase response by regulating expression of cyclic adenosine monophosphate responsive element binding protein H

(2008) Jennifer Luebke-Wheeler et al.   HEPATOLOGY

Should peripheral CB1 cannabinoid receptors be selectively targeted for therapeutic gain?

(2008) George Kunos et al.   TRENDS IN PHARMACOLOGICAL SCIENCES