Serine Phosphorylation of the Insulin-like Growth Factor I (IGF-1) Receptor C-terminal Tail Restrains Kinase Activity and Cell Growth

RACK1, A multifaceted scaffolding protein: Structure and function

(2011) David R Adams et al.   Cell Communication and Signaling

Bioinformatic Prediction and Confirmation of β-Adducin as a Novel Substrate of Glycogen Synthase Kinase 3

(2011) Hovik Farghaian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proline isosteres in a series of 2,4-disubstituted pyrrolo[1,2-f][1,2,4]triazine inhibitors of IGF-1R kinase and IR kinase

(2010) Anthony J. Sampognaro et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design of Potent IGF1-R Inhibitors Related to Bis-azaindoles

(2010) Conception Nemecek et al.   Chemical Biology & Drug Design

A kinesin signaling complex mediates the ability of GSK-3  to affect mood-associated behaviors

(2010) J. Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Selectivity of Receptor Tyrosine Kinase Signaling Is Controlled by a Secondary SH2 Domain Binding Site

(2009) Jae Hyun Bae et al.   CELL

Phosphorylation of RACK1 on Tyrosine 52 by c-Abl Is Required for Insulin-like Growth Factor I-mediated Regulation of Focal Adhesion Kinase

(2009) Patrick A. Kiely et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Discovery of a 2,4-Disubstituted Pyrrolo[1,2-f][1,2,4]triazine Inhibitor (BMS-754807) of Insulin-like Growth Factor Receptor (IGF-1R) Kinase in Clinical Development

(2009) Mark D. Wittman et al.   JOURNAL OF MEDICINAL CHEMISTRY

Emerging role of insulin-like growth factor receptor inhibitors in oncology: early clinical trial results and future directions

(2009) A Gualberto et al.   ONCOGENE

Lead identification to generate isoquinolinedione inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment

(2008) Scott C. Mayer et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Lead identification to generate 3-cyanoquinoline inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment

(2008) Lori M. Miller et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Small-molecule inhibition and activation-loop trans-phosphorylation of the IGF1 receptor

(2008) Jinhua Wu et al.   EMBO JOURNAL

Unique and Overlapping Functions of GSK-3 Isoforms in Cell Differentiation and Proliferation and Cardiovascular Development

(2008) Thomas Force et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deletion of GSK-3β in mice leads to hypertrophic cardiomyopathy secondary to cardiomyoblast hyperproliferation

(2008) Risto Kerkela et al.   JOURNAL OF CLINICAL INVESTIGATION