Article
Mechanics
Gaurav Sharma, Rajneesh Bhardwaj
Summary: This study numerically investigates the vibration response of elastically coupled tandem cylinders under transverse flow, and compares it with the classic elastically mounted cylinders. The results show that the coupled cylinders exhibit in-phase and out-of-phase vibration modes, with higher energy harvesting potential.
JOURNAL OF FLUID MECHANICS
(2023)
Article
Materials Science, Multidisciplinary
S. Chiroli, D. Faurie, M. Haboussi, A. O. Adeyeye, F. Zighem
Summary: Elastically strained ferromagnetic objects were studied using micromagnetic-mechanical numerical simulations. Temporal evolution of magnetization and modal frequency analysis of ferromagnetic thin films and nanostructure arrays were presented. Micromagnetic equations were numerically coupled with solid mechanics equations using periodic boundary conditions. Simulation results demonstrated significant disparities in magnetic mode energies due to the heterogeneity of strain fields and magnetic mode profiles, suggesting potential applications for controlling spin-wave energies based on applied elastic strains.
Article
Multidisciplinary Sciences
Cesar Manchein, Tulio M. de Oliveira, Rafael M. da Silva, Marcus W. Beims
Summary: This study explores collective transient ratchet transport in coupled ratchet systems, revealing the increase of large transient ratchet currents with the number of particles in the system and the decrease with the coupling strength between the ratchets.
SCIENTIFIC REPORTS
(2021)
Article
Physics, Multidisciplinary
Riccardo Pennetta, Martin Blaha, Aisling Johnson, Daniel Lechner, Philipp Schneeweiss, Juergen Volz, Arno Rauschenbeutel
Summary: This article experimentally and theoretically investigates collective radiative effects in an ensemble of cold atoms coupled to a single-mode optical nanofiber. The results reveal the microscopic dynamics of the system and the progressive growth of collective interactions between atoms and a guided photon. The experimental measurements demonstrate superradiant decays in the forward-propagating guided mode and the progressive growth of the collective response of the atomic ensemble.
PHYSICAL REVIEW LETTERS
(2022)
Article
Physics, Fluids & Plasmas
V. M. Rozenbaum, T. Ye. Korochkova, I. V. Shapochkina, L. I. Trakhtenberg
Summary: The motion of a Brownian particle in a sawtooth potential modulated by a spatially harmonic perturbation is studied, obtaining an explicit expression for the Laplace transform of the Green function. Integration of the relations for the average particle velocity within the approximation of small potential-energy fluctuations is performed. Results show that in such a system, controlling the magnitude and direction of the ratchet velocity is possible through the frequency-temperature interaction.
Article
Biochemistry & Molecular Biology
Marco Caremani, Massimo Reconditi
Summary: In order to understand the mechanics and energetics of the myosin motor action in muscles, it is important to determine key parameters such as motor stiffness and force, as well as the proportion of attached motors during contraction. Using sarcomere-level mechanics and a mechanical/structural model, this study found that the stiffness of a myosin dimer with both motors attached is twice that of a single motor, and that this stiffness is determined by the anisotropic and higher axial stiffness of the myosin motor.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Mathematics, Applied
Y. O. U. N. G. M. I. N. Park, P. R. A. S. H. A. N. T. Singh, Thomas G. Fai
Summary: This article investigates the dynamics of membrane vesicle motor transport into dendritic spines in neurons using an agent-based model and coarse-graining method. The study confirms that the coarse-grained model captures the bistability in velocity and waiting-time distributions observed in experiments. The results provide a new formulation for the translocation problem.
SIAM JOURNAL ON APPLIED MATHEMATICS
(2022)
Article
Nanoscience & Nanotechnology
Michael Kathan, Stefano Crespi, Niklas O. Thiel, Daniel L. Stares, Denis Morsa, John de Boer, Gianni Pacella, Tobias van den Enk, Piermichele Kobauri, Giuseppe Portale, Christoph A. Schalley, Ben L. Feringa
Summary: In this study, researchers reported a light-fuelled small-molecule ratchet capable of driving a coupled chemical equilibrium energetically uphill. By bridging imine macrocycles with a molecular motor, the machine can adopt different topologies, allowing for the coupling of continuous mechanical motion with a chemical transformation.
NATURE NANOTECHNOLOGY
(2022)
Article
Physics, Fluids & Plasmas
Inrok Oh, Jeongeun Song, Hye Ree Hyun, Sang Hak Lee, Jun Soo Kim
Summary: This study proposes a method of directional transport of nanometer-sized particles along DNA by adjusting the flexibility gradient of DNA. Experimental results show that stretching and relaxation of the DNA molecule can tune the asymmetric potentials for DNA-nanoparticle binding, leading to directional movement of nanometer-sized particles.
Review
Cell Biology
Jenna R. Christensen, Samara L. Reck-Peterson
Summary: Eukaryotic cells organize their subcellular components via intracellular transport mechanisms. Hitchhiking, a newly discovered mode of intracellular transport, involves cargos attaching to already-motile cargos. This behavior has been shown to impact cellular processes and play a significant role in cellular and evolutionary importance in different contexts.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Article
Mechanics
Yuanhang Zhu, Varghese Mathai, Kenneth Breuer
Summary: The study experimentally investigates the nonlinear fluid damping of a rigid but elastically mounted pitching wing in the absence of a free-stream flow, proposing a universal fluid damping scaling to incorporate different parameters. The fluid damping coefficient is measured from damped oscillations over a wide range of conditions, and flow fields obtained using particle image velocimetry are analysed to explain the nonlinear behaviors of the fluid damping.
JOURNAL OF FLUID MECHANICS
(2021)
Article
Physics, Multidisciplinary
Yao Wang, Yu-Ying Liu, Jian Liang, Peng-Ye Wang, Ping Xie
Summary: Cooperative transport by multiple kinesin motors was studied using stochastic simulations, revealing that the asymmetric form of unbinding rate provides better agreement with experimental data compared to the symmetric form. Additionally, for two different speed motors, the asymmetric form results in larger velocity and longer run length, explaining why kinesin adopts this form. The study also showed that the rebinding rate affects the run length of cooperative transport.
COMMUNICATIONS IN THEORETICAL PHYSICS
(2021)
Article
Physics, Fluids & Plasmas
Pedro J. Martinez, Ricardo Chacon
Summary: Directed ratchet transport can be observed in dissipative coupled systems without external bias due to unidirectional coupling of oscillatory degrees of freedom. The optimal enhancement of ratchet transport occurs when the initial conditions and parameters of these ratcheting degrees of freedom are suitably chosen as predicted by the theory of ratchet universality. This autonomous ratchet scenario has technological applications and is relevant for studies of molecular motors in the biological realm.
Article
Acoustics
Rajan Prasad, Arnab Banerjee
Summary: This study investigates flexural wave propagation in elastically coupled telescopic metabeams and models it using distributed elastic springs. It is found that tuning the stiffness and length ratio of the metabeam can significantly widen the attenuation bandwidth in low frequencies without adding any additional masses or resonators to the structure.
JOURNAL OF VIBRATION AND ACOUSTICS-TRANSACTIONS OF THE ASME
(2021)
Article
Physics, Fluids & Plasmas
A. Caumont, O. Stephan, E. Bossy, B. Dollet, C. Quilliet, P. Marmottant
Summary: Gas bubbles stabilized in toroidal 3D-printed cages exhibit unusual topology and serve as good acoustic resonators. Organizing them in a circular array forms an acoustic tokamak due to its torus shape. Experimentally and theoretically, it is shown that the system has multiple acoustic modes resulting from the acoustic interaction between tori. The fundamental acoustic mode has a significantly lower frequency than that of individual bubbles, and the acoustic field inside the acoustic tokamak is remarkably homogeneous according to our 3D simulations.
Article
Biochemistry & Molecular Biology
Artem K. Efremov, Yuanyuan Qu, Hugo Maruyama, Ci J. Lim, Kunio Takeyasu, Jie Yan
JOURNAL OF BIOLOGICAL CHEMISTRY
(2015)
Article
Biochemistry & Molecular Biology
Shimin Le, Mingxi Yao, Jin Chen, Artem K. Efremov, Sara Azimi, Jie Yan
NUCLEIC ACIDS RESEARCH
(2015)
Article
Multidisciplinary Sciences
Miao Yu, Xin Yuan, Chen Lu, Shimin Le, Ryo Kawamura, Artem K. Efremov, Zhihai Zhao, Michael M. Kozlov, Michael Sheetz, Alexander Bershadsky, Jie Yan
NATURE COMMUNICATIONS
(2017)
Review
Polymer Science
Artem K. Efremov, Ricksen S. Winardhi, Jie Yan
News Item
Biophysics
Artem K. Efremov, Fazoil I. Ataullakhanov
BIOPHYSICAL JOURNAL
(2018)
Article
Chemistry, Multidisciplinary
Miao Yu, Shimin Le, Artem K. Efremov, Xiangjun Zeng, Alexander Bershadsky, Jie Yan
Article
Biochemistry & Molecular Biology
Artem K. Efremov, Jie Yan
NUCLEIC ACIDS RESEARCH
(2018)
Article
Biochemistry & Molecular Biology
Huijuan You, Xiangjun Zeng, Yue Xu, Ci Ji Lim, Artem K. Efremov, Anh Tuan Phan, Jie Yan
NUCLEIC ACIDS RESEARCH
(2014)
Article
Multidisciplinary Sciences
Artem K. Efremov, Anand Radhakrishnan, David S. Tsao, Carol S. Bookwalter, Kathleen M. Trybus, Michael R. Diehl
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2014)
Article
Multidisciplinary Sciences
N. O. Alieva, A. K. Efremov, S. Hu, D. Oh, Z. Chen, M. Natarajan, H. T. Ong, A. Jegou, G. Romet-Lemonne, J. T. Groves, M. P. Sheetz, J. Yan, A. D. Bershadsky
NATURE COMMUNICATIONS
(2019)
Article
Engineering, Biomedical
Artem K. Efremov, Mingxi Yao, Yuze Sun, Yee Han Tee, Michael P. Sheetz, Alexander D. Bershadsky, Boris Martinac, Jie Yan
Summary: This study verifies the mechanosensitivity of L-type Ca2+ channels in Filopodia and reveals the interplay between mechanical forces and Ca2+ signaling in Filopodia, providing novel mechanistic insights into the guidance function of Filopodia in cell migration.
Article
Biophysics
Yunxin Deng, Artem K. Efremov, Jie Yan
Summary: Proteins rely on specific interactions with binding partners for their biological functions. Proteins with multiple binding domains can significantly enhance both the binding affinity and specificity, as well as lower the working concentration range. Positive domain-domain cooperativity or the presence of a non-specific binding domain can decrease the working concentration range by increasing the binding affinity without compromising the binding specificity. The configuration of bound ligands shows concentration dependence, providing insights into phase-separation processes in living cells.
BIOPHYSICAL JOURNAL
(2022)
Article
Biophysics
Artem K. Efremov, Ladislav Hovan, Jie Yan
Summary: The size of the nucleus affects DNA-protein interactions and chromatin structure, which is determined by the difference in surface tensions between the nuclear envelope and endoplasmic reticulum membrane, as well as the osmotic pressure exerted by cytosolic macromolecules. The cell nucleus also functions as a piezoelectric element, changing its electrostatic potential in a size-dependent manner and affecting the stability of nucleosomes.
BIOPHYSICAL JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Shiwen Guo, Artem K. Efremov, Jie Yan
COMMUNICATIONS CHEMISTRY
(2019)
Article
Physics, Fluids & Plasmas
Artem K. Efremov, Ricksen S. Winardhi, Jie Yan