Bispecific Designed Ankyrin Repeat Proteins (DARPins) Targeting Epidermal Growth Factor Receptor Inhibit A431 Cell Proliferation and Receptor Recycling

DARPins and other repeat protein scaffolds: advances in engineering and applications

(2011) Ykelien L Boersma et al.   CURRENT OPINION IN BIOTECHNOLOGY

Non-immunoglobulin based protein scaffolds

(2011) John Löfblom et al.   CURRENT OPINION IN BIOTECHNOLOGY

A biparatopic anti-EGFR nanobody efficiently inhibits solid tumour growth

(2011) Rob C. Roovers et al.   INTERNATIONAL JOURNAL OF CANCER

Enhanced EGFR inhibition and distinct epitope recognition by EGFR antagonistic MABS C225 and 425

(2010) Vishal Kamat et al.   CANCER BIOLOGY & THERAPY

Efficient Tumor Targeting with High-Affinity Designed Ankyrin Repeat Proteins: Effects of Affinity and Molecular Size

(2010) C. Zahnd et al.   CANCER RESEARCH

Sym004: A Novel Synergistic Anti-Epidermal Growth Factor Receptor Antibody Mixture with Superior Anticancer Efficacy

(2010) M. W. Pedersen et al.   CANCER RESEARCH

A Novel Fusion Toxin Derived from an EpCAM-Specific Designed Ankyrin Repeat Protein Has Potent Antitumor Activity

(2010) P. Martin-Killias et al.   CLINICAL CANCER RESEARCH

Combination antibody treatment down-regulates epidermal growth factor receptor by inhibiting endosomal recycling

(2010) J. B. Spangler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epidermal growth factor receptor lacking C-terminal autophosphorylation sites retains signal transduction and high sensitivity to epidermal growth factor receptor tyrosine kinase inhibitor

(2009) Mari Maegawa et al.   CANCER SCIENCE

ErbB receptors and signaling pathways in cancer

(2009) Nancy E Hynes et al.   CURRENT OPINION IN CELL BIOLOGY

Different antiproliferative effects of matuzumab and cetuximab in A431 cells are associated with persistent activity of the MAPK pathway

(2009) Debora Dummer Meira et al.   EUROPEAN JOURNAL OF CANCER

A novel anti-EGFR monoclonal antibody inhibiting tumor cell growth by recognizing different epitopes from cetuximab

(2009) Kwang-Won Hong et al.   JOURNAL OF BIOTECHNOLOGY

EpCAM-targeted delivery of nanocomplexed siRNA to tumor cells with designed ankyrin repeat proteins

(2009) J. Winkler et al.   MOLECULAR CANCER THERAPEUTICS

Antibodies specifically targeting a locally misfolded region of tumor associated EGFR

(2009) T. P. J. Garrett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Matuzumab Binding to EGFR Prevents the Conformational Rearrangement Required for Dimerization

(2008) Judith Schmiedel et al.   CANCER CELL

Membrane-anchored growth factors, the epidermal growth factor family: Beyond receptor ligands

(2008) Shigeki Higashiyama et al.   CANCER SCIENCE

Interaction of antibodies with ErbB receptor extracellular regions

(2008) Karl R. Schmitz et al.   EXPERIMENTAL CELL RESEARCH

EGFR family: Structure physiology signalling and therapeutic targets†

(2008) Antony W. Burgess   GROWTH FACTORS

ErbB-directed immunotherapy: Antibodies in current practice and promising new agents

(2008) Elza Friedländer et al.   IMMUNOLOGY LETTERS

ErbB receptors, their ligands, and the consequences of their activation and inhibition in the myocardium

(2008) Stephen J. Fuller et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Efficient Selection of DARPins with Sub-nanomolar Affinities using SRP Phage Display

(2008) Daniel Steiner et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural Basis for EGF Receptor Inhibition by the Therapeutic Antibody IMC-11F8

(2008) Shiqing Li et al.   STRUCTURE