Oligomerization of DNMT3A Controls the Mechanism ofde NovoDNA Methylation

Determinants of Precatalytic Conformational Transitions in the DNA Cytosine Methyltransferase M.HhaI

(2011) Douglas M. Matje et al.   BIOCHEMISTRY

Regulation of mammalian DNA methyltransferases: a route to new mechanisms

(2011) Hélène Denis et al.   EMBO REPORTS

Recurrent DNMT3A mutations in patients with myelodysplastic syndromes

(2011) M J Walter et al.   LEUKEMIA

DNMT3A mutations in acute myeloid leukemia

(2011) Mrinal Y Shah et al.   NATURE GENETICS

Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia

(2011) Xiao-Jing Yan et al.   NATURE GENETICS

Modulation of Dnmt3b function in vitro by interactions with Dnmt3L, Dnmt3a and Dnmt3b splice variants

(2011) Beth O. Van Emburgh et al.   NUCLEIC ACIDS RESEARCH

Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1)

(2011) K. Takeshita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a second DNA binding site in human DNA methyltransferase 3A by substrate inhibition and domain deletion

(2010) Matthew M. Purdy et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Dnmt3/transcription factor interactions as crucial players in targeted DNA methylation

(2010) Eric Hervouet et al.   Epigenetics

The Inherent Processivity of the Humande NovoMethyltransferase 3A (DNMT3A) Is Enhanced by DNMT3L

(2010) Celeste Holz-Schietinger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DNMT3AMutations in Acute Myeloid Leukemia

(2010) Timothy J. Ley et al.   NEW ENGLAND JOURNAL OF MEDICINE

Structure of DNMT1-DNA Complex Reveals a Role for Autoinhibition in Maintenance DNA Methylation

(2010) J. Song et al.   SCIENCE

Dnmt3a-Dependent Nonpromoter DNA Methylation Facilitates Transcription of Neurogenic Genes

(2010) H. Wu et al.   SCIENCE

Dimeric/oligomeric DNA methyltransferases: an unfinished story

(2009) Ernst G. Malygin et al.   BIOLOGICAL CHEMISTRY

CXXC Domain of Human DNMT1 Is Essential for Enzymatic Activity

(2008) Mihika Pradhan et al.   BIOCHEMISTRY

Small RNA guides for de novo DNA methylation in mammalian germ cells

(2008) A. A. Aravin et al.   GENES & DEVELOPMENT

Establishing a Mechanistic Basis for the Large Kinetic Steps of the NS3 Helicase

(2008) Victor Serebrov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The RosettaDock server for local protein-protein docking

(2008) S. Lyskov et al.   NUCLEIC ACIDS RESEARCH

Mammalian DNA Methyltransferases: A Structural Perspective

(2008) Xiaodong Cheng et al.   STRUCTURE