The Giant Protein Titin: A Regulatory Node That Integrates Myocyte Signaling Pathways

Molecular basis of the head-to-tail assembly of giant muscle proteins obscurin-like 1 and titin

(2010) Florian Sauer et al.   EMBO REPORTS

Roles of Titin in the Structure and Elasticity of the Sarcomere

(2010) Larissa Tskhovrebova et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Calcium sensitivity and the Frank–Starling mechanism of the heart are increased in titin N2B region-deficient mice

(2010) Eun-Jeong Lee et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The Structure of the FnIII Tandem A77-A78 Points to a Periodically Conserved Architecture in the Myosin-Binding Region of Titin

(2010) Rainer M. Bucher et al.   JOURNAL OF MOLECULAR BIOLOGY

Shape and Flexibility in the Titin 11-Domain Super-Repeat

(2010) Larissa Tskhovrebova et al.   JOURNAL OF MOLECULAR BIOLOGY

The Giant Protein Titin as an Integrator of Myocyte Signaling Pathways

(2010) Wolfgang A. Linke et al.   PHYSIOLOGY

Structural insight into M-band assembly and mechanics from the titin-obscurin-like-1 complex

(2010) S. Pernigo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tuning Passive Mechanics through Differential Splicing of Titin during Skeletal Muscle Development

(2009) Coen A.C. Ottenheijm et al.   BIOPHYSICAL JOURNAL

PKC Phosphorylation of Titin’s PEVK Element

(2009) Carlos Hidalgo et al.   CIRCULATION RESEARCH

Hypophosphorylation of the Stiff N2B Titin Isoform Raises Cardiomyocyte Resting Tension in Failing Human Myocardium

(2009) Attila Borbély et al.   CIRCULATION RESEARCH

Hsp27 associates with the titin filament system in heat-shocked zebrafish cardiomyocytes

(2009) Nathan R. Tucker et al.   EXPERIMENTAL CELL RESEARCH

Single Molecule Force Spectroscopy of the Cardiac Titin N2B Element

(2009) Yi Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bin1 Src Homology 3 Domain Acts as a Scaffold for Myofiber Sarcomere Assembly

(2009) Pasan Fernando et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Titin-based mechanical signalling in normal and failing myocardium

(2009) Martina Krüger et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Excision of titin's cardiac PEVK spring element abolishes PKCα-induced increases in myocardial stiffness

(2009) Bryan D. Hudson et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The titin-telethonin complex is a directed, superstable molecular bond in the muscle Z-disk

(2009) M. Bertz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanical Network in Titin Immunoglobulin from Force Distribution Analysis

(2009) Wolfram Stacklies et al.   PLoS Computational Biology

Calpain 1 Binding Capacities of the N1-Line Region of Titin Are Significantly Enhanced by Physiological Concentrations of Calcium†

(2008) Gerald Coulis et al.   BIOCHEMISTRY

Build it up-Tear it down: protein quality control in the cardiac sarcomere

(2008) M. S. Willis et al.   CARDIOVASCULAR RESEARCH

Protein Kinase G Modulates Human Myocardial Passive Stiffness by Phosphorylation of the Titin Springs

(2008) Martina Krüger et al.   CIRCULATION RESEARCH

Multiple Molecular Interactions Implicate the Connectin/Titin N2A Region as a Modulating Scaffold for p94/Calpain 3 Activity in Skeletal Muscle

(2008) Chikako Hayashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiplex Kinase Signaling Modifies Cardiac Function at the Level of Sarcomeric Proteins

(2008) R. John Solaro   JOURNAL OF BIOLOGICAL CHEMISTRY

An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice

(2008) Farah Sheikh et al.   JOURNAL OF CLINICAL INVESTIGATION

Troponin and Titin Coordinately Regulate Length-dependent Activation in Skinned Porcine Ventricular Muscle

(2008) Takako Terui et al.   JOURNAL OF GENERAL PHYSIOLOGY

Mutation that dramatically alters rat titin isoform expression and cardiomyocyte passive tension

(2008) Marion L. Greaser et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Evidence for the Oligomeric State of ‘Elastic’ Titin in Muscle Sarcomeres

(2008) Ahmed Houmeida et al.   JOURNAL OF MOLECULAR BIOLOGY

Mechanoenzymatics of titin kinase

(2008) E. M. Puchner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A regular pattern of Ig super-motifs defines segmental flexibility as the elastic mechanism of the titin chain

(2008) E. von Castelmur et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Three-dimensional structure of vertebrate cardiac muscle myosin filaments

(2008) M. E. Zoghbi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA