Identification of Essential Cannabinoid-binding Domains

Crystal structure of metarhodopsin II

(2011) Hui-Woog Choe et al.   NATURE

The structural basis of agonist-induced activation in constitutively active rhodopsin

(2011) Jörg Standfuss et al.   NATURE

Structure of a nanobody-stabilized active state of the β2 adrenoceptor

(2011) Søren G. F. Rasmussen et al.   NATURE

The endocannabinoid system as a target for the treatment of neurodegenerative disease

(2010) Emma L Scotter et al.   BRITISH JOURNAL OF PHARMACOLOGY

CB1 Cannabinoid Receptors and their Associated Proteins

(2010) Allyn Howlett et al.   CURRENT MEDICINAL CHEMISTRY

Understanding Functional Residues of the Cannabinoid CB1 Receptor for Drug Discovery

(2010) Joong-Youn Shim   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Distinct second extracellular loop structures of the brain cannabinoid CB1 receptor: Implication in ligand binding and receptor function

(2010) Joong-Youn Shim et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Location, Structure, and Dynamics of the Synthetic Cannabinoid Ligand CP-55,940 in Lipid Bilayers

(2009) Tomohiro Kimura et al.   BIOPHYSICAL JOURNAL

Transmembrane Helical Domain of the Cannabinoid CB1 Receptor

(2009) Joong-Youn Shim   BIOPHYSICAL JOURNAL

A Conserved Aromatic Lock for the Tryptophan Rotameric Switch in TM-VI of Seven-transmembrane Receptors

(2009) Birgitte Holst et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Light Activation of Rhodopsin: Insights from Molecular Dynamics Simulations Guided by Solid-State NMR Distance Restraints

(2009) Viktor Hornak et al.   JOURNAL OF MOLECULAR BIOLOGY

Dual Role of the Second Extracellular Loop of the Cannabinoid Receptor 1: Ligand Binding and Receptor Localization

(2009) K. H. Ahn et al.   MOLECULAR PHARMACOLOGY

Cannabinoids as pharmacotherapies for neuropathic pain: From the bench to the bedside

(2009) Elizabeth J. Rahn et al.   Neurotherapeutics

Distribution of Amino Acids in a Lipid Bilayer from Computer Simulations

(2008) Justin L. MacCallum et al.   BIOPHYSICAL JOURNAL

Cannabinoid CB1 and CB2 Receptor Ligand Specificity and the Development of CB2-Selective Agonists

(2008) John Ashton et al.   CURRENT MEDICINAL CHEMISTRY

Structure of a β1-adrenergic G-protein-coupled receptor

(2008) Tony Warne et al.   NATURE

Crystal structure of opsin in its G-protein-interacting conformation

(2008) Patrick Scheerer et al.   NATURE

Crystal structure of the ligand-free G-protein-coupled receptor opsin

(2008) Jung Hee Park et al.   NATURE

High-resolution distance mapping in rhodopsin reveals the pattern of helix movement due to activation

(2008) C. Altenbach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist

(2008) V.-P. Jaakola et al.   SCIENCE

Involvement of the Carboxyl Terminus of the Third Intracellular Loop of the Cannabinoid CB1 Receptor in Constitutive Activation of Gs

(2003) Vasiliki Abadji et al.   JOURNAL OF NEUROCHEMISTRY