Mechanistic Insights into Specificity, Activity, and Regulatory Elements of the Regulator of G-protein Signaling (RGS)-containing Rho-specific Guanine Nucleotide Exchange Factors (GEFs) p115, PDZ-RhoGEF (PRG), and Leukemia-associated RhoGEF (LARG)

Structural and Energetic Mechanisms of Cooperative Autoinhibition and Activation of Vav1

(2010) Bingke Yu et al.   CELL

A conserved hydrophobic surface of the LARG pleckstrin homology domain is critical for RhoA activation in cells

(2009) Mohamed Aittaleb et al.   CELLULAR SIGNALLING

Real-time NMR Study of Guanine Nucleotide Exchange and Activation of RhoA by PDZ-RhoGEF

(2009) Geneviève M. C. Gasmi-Seabrook et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure and Function of Heterotrimeric G Protein-Regulated Rho Guanine Nucleotide Exchange Factors

(2009) M. Aittaleb et al.   MOLECULAR PHARMACOLOGY

The solution structure and dynamics of the DH-PH module of PDZRhoGEF in isolation and in complex with nucleotide-free RhoA

(2009) Tomasz Cierpicki et al.   PROTEIN SCIENCE

On the mechanism of autoinhibition of the RhoA-specific nucleotide exchange factor PDZRhoGEF

(2009) Meiying Zheng et al.   BMC STRUCTURAL BIOLOGY

Internal dynamics control activation and activity of the autoinhibited Vav DH domain

(2008) Pilong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY