Targeting the Warburg Effect That Arises in Tumor Cells Expressing Membrane Type-1 Matrix Metalloproteinase

Membrane Type 1-Matrix Metalloproteinase Cleaves Off the NH2-Terminal Portion of Heparin-Binding Epidermal Growth Factor and Converts It into a Heparin-Independent Growth Factor

(2010) N. Koshikawa et al.   CANCER RESEARCH

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

(2010) Kai Kessenbrock et al.   CELL

A Membrane Protease Regulates Energy Production in Macrophages by Activating Hypoxia-inducible Factor-1 via a Non-proteolytic Mechanism

(2010) Takeharu Sakamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Navigating ECM Barriers at the Invasive Front: The Cancer Cell–Stroma Interface

(2009) R. Grant Rowe et al.   Annual Review of Cell and Developmental Biology

Matrix metalloproteinase proteomics: substrates, targets, and therapy

(2009) Charlotte J Morrison et al.   CURRENT OPINION IN CELL BIOLOGY

HIF-1: upstream and downstream of cancer metabolism

(2009) Gregg L Semenza   CURRENT OPINION IN GENETICS & DEVELOPMENT

Cytoplasmic tail of MT1-MMP regulates macrophage motility independently from its protease activity

(2009) Takeharu Sakamoto et al.   GENES TO CELLS

Mint3 Enhances the Activity of Hypoxia-inducible Factor-1 (HIF-1) in Macrophages by Suppressing the Activity of Factor Inhibiting HIF-1

(2009) Takeharu Sakamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Defining the role of laminin-332 in carcinoma

(2009) Cherise M. Guess et al.   MATRIX BIOLOGY

HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer

(2009) Charles J. David et al.   NATURE

Induction of a MT1-MMP and MT2-MMP-dependent basement membrane transmigration program in cancer cells by Snail1

(2009) I. Ota et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tyrosine Phosphorylation Inhibits PKM2 to Promote the Warburg Effect and Tumor Growth

(2009) T. Hitosugi et al.   Science Signaling

PKM2 Tyrosine Phosphorylation and Glutamine Metabolism Signal a Different View of the Warburg Effect

(2009) C. V. Dang   Science Signaling

Tumor Cell Metabolism: Cancer's Achilles' Heel

(2008) Guido Kroemer et al.   CANCER CELL

Interaction of Mint3 with Furin regulates the localization of Furin in the trans-Golgi network

(2008) J. Han et al.   JOURNAL OF CELL SCIENCE

Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway

(2008) William G. Kaelin et al.   MOLECULAR CELL

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

(2008) Heather R. Christofk et al.   NATURE

p53 regulates glucose metabolism through an IKK-NF-κB pathway and inhibits cell transformation

(2008) Keiko Kawauchi et al.   NATURE CELL BIOLOGY

Breaching the basement membrane: who, when and how?

(2008) R. Grant Rowe et al.   TRENDS IN CELL BIOLOGY