Dynamic Ligand-induced Conformational Rearrangements in P-glycoprotein as Probed by Fluorescence Resonance Energy Transfer Spectroscopy

Molecular-Dynamics Simulations of the ATP/apo State of a Multidrug ATP-Binding Cassette Transporter Provide a Structural and Mechanistic Basis for the Asymmetric Occluded State

(2011) Peter M. Jones et al.   BIOPHYSICAL JOURNAL

P-glycoprotein Retains Drug-stimulated ATPase Activity upon Covalent Linkage of the Two Nucleotide Binding Domains at Their C-terminal Ends

(2011) Brandy Verhalen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reaction chemistry ABC-style

(2011) A. E. Senior   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Snapshots of the maltose transporter during ATP hydrolysis

(2011) M. L. Oldham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human P-glycoprotein is active when the two halves are clamped together in the closed conformation

(2010) Tip W. Loo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Single-molecule fluorescence resonance energy transfer techniques on rotary ATP synthases

(2010) Michael Börsch   BIOLOGICAL CHEMISTRY

Characterization of an Asymmetric Occluded State of P-glycoprotein with Two Bound Nucleotides

(2010) Alena Siarheyeva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamics of  -helical subdomain rotation in the intact maltose ATP-binding cassette transporter

(2010) C. Orelle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanistic basis for differential inhibition of the F1Fo-ATPase by aurovertin

(2009) Kathryn M. Johnson et al.   BIOPOLYMERS

The ATP-binding cassette family: a structural perspective

(2009) Veronica Kos et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

36° step size of proton-driven c-ring rotation in FoF1-ATP synthase

(2009) Monika G Düser et al.   EMBO JOURNAL

ABC transporters: the power to change

(2009) Douglas C. Rees et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

(2009) S. G. Aller et al.   SCIENCE

ABC transporters: a riddle wrapped in a mystery inside an enigma

(2009) Peter M. Jones et al.   TRENDS IN BIOCHEMICAL SCIENCES

Understanding polyspecificity of multidrug ABC transporters: closing in on the gaps in ABCB1

(2009) Daniel A.P. Gutmann et al.   TRENDS IN BIOCHEMICAL SCIENCES

The Proton-translocatingaSubunit of F0F1-ATP Synthase Is Allocated Asymmetrically to the Peripheral Stalk

(2008) Monika G. Düser et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ABC multidrug transporters: structure, function and role in chemoresistance

(2007) Frances J Sharom   PHARMACOGENOMICS