Metalloproteinase-mediated Shedding of Integrin β2 Promotes Macrophage Efflux from Inflammatory Sites

Cleavage of the CD11b extracellular domain by the leukocyte serprocidins is critical for neutrophil detachment during chemotaxis

(2011) K. Zen et al.   BLOOD

Adam17-dependent shedding limits early neutrophil influx but does not alter early monocyte recruitment to inflammatory sites

(2011) J. Tang et al.   BLOOD

Molecular Basis for the Interaction of Low Density Lipoprotein Receptor-related Protein 1 (LRP1) with Integrin αMβ2

(2011) Sripriya Ranganathan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Saturated-efferocytosis generates pro-resolving CD11blow macrophages: Modulation by resolvins and glucocorticoids

(2010) Sagie Schif-Zuck et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

ADAM10 is essential for Notch2-dependent marginal zone B cell development and CD23 cleavage in vivo

(2010) David R. Gibb et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Shedding of Large Functionally Active CD11/CD18 Integrin Complexes from Leukocyte Membranes during Synovial Inflammation Distinguishes Three Types of Arthritis through Differential Epitope Exposure

(2010) L. C. Gjelstrup et al.   JOURNAL OF IMMUNOLOGY

Outside-In Signal Transmission by Conformational Changes in Integrin Mac-1

(2009) C. T. Lefort et al.   JOURNAL OF IMMUNOLOGY

Inflammatory macrophage migration requires MMP-9 activation by plasminogen in mice

(2008) Yanqing Gong et al.   JOURNAL OF CLINICAL INVESTIGATION

MMP-9 Sheds the β2Integrin Subunit (CD18) from Macrophages

(2008) Tomáš Vaisar et al.   MOLECULAR & CELLULAR PROTEOMICS

The “A Disintegrin And Metalloprotease” (ADAM) family of sheddases: Physiological and cellular functions

(2008) Karina Reiss et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Clipping, shedding and RIPping keep immunity on cue

(2008) Gillian Murphy et al.   TRENDS IN IMMUNOLOGY