A Novel Role for Interleukin-27 (IL-27) as Mediator of Intestinal Epithelial Barrier Protection Mediated via Differential Signal Transducer and Activator of Transcription (STAT) Protein Signaling and Induction of Antibacterial and Anti-inflammatory Proteins

Inflamed Intestinal Mucosa Features a Specific Epithelial Expression Pattern of Indoleamine 2,3-Dioxygenase

(2017) L. Ferdinande et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Interleukin-35 Mediates Mucosal Immune Responses That Protect Against T-Cell–Dependent Colitis

(2011) Stefan Wirtz et al.   GASTROENTEROLOGY

DMBT1 is a novel gene induced by IL-22 in ulcerative colitis

(2010) Hirokazu Fukui et al.   INFLAMMATORY BOWEL DISEASES

Interleukin-27 Induces a STAT1/3- and NF-κB-dependent Proinflammatory Cytokine Profile in Human Monocytes

(2010) Christina Guzzo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Induction of IDO-1 by Immunostimulatory DNA Limits Severity of Experimental Colitis

(2010) M. A. Ciorba et al.   JOURNAL OF IMMUNOLOGY

Indoleamine 2,3-Dioxygenase Mediates the Antiviral Effect of Gamma Interferon against Hepatitis B Virus in Human Hepatocyte-Derived Cells

(2010) R. Mao et al.   JOURNAL OF VIROLOGY

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

Serotonin Has a Key Role in Pathogenesis of Experimental Colitis

(2009) Jean–Eric Ghia et al.   GASTROENTEROLOGY

Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease

(2009) S. Brand   GUT

Leucine-rich Repeats of Bacterial Surface Proteins Serve as Common Pattern Recognition Motifs of Human Scavenger Receptor gp340

(2009) Vuokko Loimaranta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential Effect of IL-27 on Developing versus Committed Th17 Cells

(2009) M. El-behi et al.   JOURNAL OF IMMUNOLOGY

IL-27 Regulates Homeostasis of the Intestinal CD4+ Effector T Cell Pool and Limits Intestinal Inflammation in a Murine Model of Colitis

(2009) A. E. Troy et al.   JOURNAL OF IMMUNOLOGY

IL-27 Is a Key Regulator of IL-10 and IL-17 Production by Human CD4+ T Cells

(2009) G. Murugaiyan et al.   JOURNAL OF IMMUNOLOGY

IDO Activates Regulatory T Cells and Blocks Their Conversion into Th17-Like T Cells

(2009) B. Baban et al.   JOURNAL OF IMMUNOLOGY

IL-27 Blocks RORc Expression to Inhibit Lineage Commitment of Th17 Cells

(2009) C. Diveu et al.   JOURNAL OF IMMUNOLOGY

Common variants at five new loci associated with early-onset inflammatory bowel disease

(2009) Marcin Imielinski et al.   NATURE GENETICS

GP130-STAT3 Regulates Epithelial Cell Migration and Is Required for Repair of the Bronchiolar Epithelium

(2008) Hiroshi Kida et al.   AMERICAN JOURNAL OF PATHOLOGY

IL-12, IL-23, and IL-27 enhance human β-defensin-2 production in human keratinocytes

(2008) Naoko Kanda et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-27R deficiency delays the onset of colitis and protects from helminth-induced pathology in a model of chronic IBD

(2008) Alejandro V. Villarino et al.   INTERNATIONAL IMMUNOLOGY

Scavenger receptor gp340 aggregates group A streptococci by binding pili

(2008) Andrew M. Edwards et al.   MOLECULAR MICROBIOLOGY