1-Deoxy-d-xylulose 5-Phosphate Synthase Catalyzes a Novel Random Sequential Mechanism

Valine 375 and Phenylalanine 109 Confer Affinity and Specificity for Pyruvate as Donor Substrate in Acetohydroxy Acid Synthase Isozyme II fromEscherichia coli

(2010) Andrea Steinmetz et al.   BIOCHEMISTRY

Succinylphosphonate Esters Are Competitive Inhibitors of MenD That Show Active-Site Discrimination between Homologous α-Ketoglutarate-Decarboxylating Enzymes

(2010) Maohai Fang et al.   BIOCHEMISTRY

A single-molecule force spectroscopy nanosensor for the identification of new antibiotics and antimalarials

(2010) Xavier Sisquella et al.   FASEB JOURNAL

The herbicide ketoclomazone inhibits 1-deoxy-D-xylulose 5-phosphate synthase in the 2-C-methyl-D-erythritol 4-phosphate pathway and shows antibacterial activity against Haemophilus influenzae

(2010) Yukiko Matsue et al.   JOURNAL OF ANTIBIOTICS

Snapshot of a Reaction Intermediate: Analysis of Benzoylformate Decarboxylase in Complex with a Benzoylphosphonate Inhibitor†

(2009) Gabriel S. Brandt et al.   BIOCHEMISTRY

Revealing Substrate Promiscuity of 1-Deoxy-d-xylulose 5-Phosphate Synthase

(2009) Leighanne A. Brammer et al.   ORGANIC LETTERS

The Mycobacterium tuberculosis MEP (2C-methyl-d-erythritol 4-phosphate) pathway as a new drug target

(2008) Hyungjin Eoh et al.   TUBERCULOSIS