Structural and Mechanistic Implications of Metal Binding in the Small Heat-shock Protein αB-crystallin

Binding of γ-Crystallin Substrate Prevents the Binding of Copper and Zinc Ions to the Molecular Chaperone α-Crystallin

(2011) Kalyan S. Ghosh et al.   BIOCHEMISTRY

Inhibition of Cu2+-mediated generation of reactive oxygen species by the small heat shock protein αB-crystallin: The relative contributions of the N- and C-terminal domains

(2011) Sankaralingam Prabhu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Crystal Structure of R120G Disease Mutant of Human αB-Crystallin Domain Dimer Shows Closure of a Groove

(2011) A.R. Clark et al.   JOURNAL OF MOLECULAR BIOLOGY

Solid-state NMR of proteins sedimented by ultracentrifugation

(2011) I. Bertini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

N-terminal domain of  B-crystallin provides a conformational switch for multimerization and structural heterogeneity

(2011) S. Jehle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting oxidative stress in cancer

(2010) Matthew W Lawless et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Metals, oxidative stress and neurodegenerative disorders

(2010) Klaudia Jomova et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Solid-state NMR and SAXS studies provide a structural basis for the activation of αB-crystallin oligomers

(2010) Stefan Jehle et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Quaternary dynamics and plasticity underlie small heat shock protein chaperone function

(2010) F. Stengel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Improving the quality of NMR and crystallographic protein structures by means of a conformational database potential derived from structure databases

(2010) John Kuszewski et al.   PROTEIN SCIENCE

Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function

(2010) Arthur Laganowsky et al.   PROTEIN SCIENCE

Copper(II) Binding to Amyloid-β Fibrils of Alzheimer’s Disease Reveals a Picomolar Affinity: Stoichiometry and Coordination Geometry Are Independent of Aβ Oligomeric Form

(2009) Claire J. Sarell et al.   BIOCHEMISTRY

Risks of Copper and Iron Toxicity during Aging in Humans

(2009) George J. Brewer   CHEMICAL RESEARCH IN TOXICOLOGY

Cellular copper management—a draft user's guide

(2009) Ivano Bertini et al.   COORDINATION CHEMISTRY REVIEWS

Crystal Structures of α-Crystallin Domain Dimers of αB-Crystallin and Hsp20

(2009) C. Bagnéris et al.   JOURNAL OF MOLECULAR BIOLOGY

Large Protein Complexes with Extreme Rotational Correlation Times Investigated in Solution by Magic-Angle-Spinning NMR Spectroscopy

(2009) Andi Mainz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The eye lens chaperone  -crystallin forms defined globular assemblies

(2009) J. Peschek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small Heat Shock Protein Activity Is Regulated by Variable Oligomeric Substructure

(2008) Justin L. P. Benesch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective Cu2+ Binding, Redox Silencing, and Cytoprotective Effects of the Small Heat Shock Proteins αA- and αB-Crystallin

(2008) Md. Faiz Ahmad et al.   JOURNAL OF MOLECULAR BIOLOGY

αB-Crystallin: A Hybrid Solid-State/Solution-State NMR Investigation Reveals Structural Aspects of the Heterogeneous Oligomer

(2008) Stefan Jehle et al.   JOURNAL OF MOLECULAR BIOLOGY

Zn2+Enhances the Molecular Chaperone Function and Stability of α-Crystallin†

(2007) Ashis Biswas et al.   BIOCHEMISTRY