Human Mre11/Human Rad50/Nbs1 and DNA Ligase IIIα/XRCC1 Protein Complexes Act Together in an Alternative Nonhomologous End Joining Pathway

Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair

(2011) Deniz Simsek et al.   NATURE

DNA ligase III is critical for mtDNA integrity but not Xrcc1-mediated nuclear DNA repair

(2011) Yankun Gao et al.   NATURE

DNA Ligase III Promotes Alternative Nonhomologous End-Joining during Chromosomal Translocation Formation

(2011) Deniz Simsek et al.   PLoS Genetics

NHEJ and its backup pathways in chromosomal translocations

(2010) Michael R Lieber   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Alternative end-joining is suppressed by the canonical NHEJ component Xrcc4–ligase IV during chromosomal translocation formation

(2010) Deniz Simsek et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mre11–Rad50–Xrs2 and Sae2 promote 5′ strand resection of DNA double-strand breaks

(2010) Matthew L Nicolette et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70

(2010) C. Boboila et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ku Regulates the Non-Homologous End Joining Pathway Choice of DNA Double-Strand Break Repair in Human Somatic Cells

(2010) Farjana Fattah et al.   PLoS Genetics

53BP1 promotes ATM activity through direct interactions with the MRN complex

(2009) Ji-Hoon Lee et al.   EMBO JOURNAL

Phosphorylation of Human DNA Ligase I Regulates Its Interaction with Replication Factor C and Its Participation in DNA Replication and DNA Repair

(2009) S. Vijayakumar et al.   MOLECULAR AND CELLULAR BIOLOGY

Roles for NBS1 in Alternative Nonhomologous End-Joining of V(D)J Recombination Intermediates

(2009) Ludovic Deriano et al.   MOLECULAR CELL

Mechanisms promoting translocations in editing and switching peripheral B cells

(2009) Jing H. Wang et al.   NATURE

Multiple functions of MRN in end-joining pathways during isotype class switching

(2009) Maria Dinkelmann et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Role of mammalian Mre11 in classical and alternative nonhomologous end joining

(2009) Anyong Xie et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells

(2009) Emilie Rass et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Up-regulation of WRN and DNA ligase III  in chronic myeloid leukemia: consequences for the repair of DNA double-strand breaks

(2008) A. Sallmyr et al.   BLOOD

Rational Design of Human DNA Ligase Inhibitors that Target Cellular DNA Replication and Repair

(2008) X. Chen et al.   CANCER RESEARCH

The P. furiosus Mre11/Rad50 Complex Promotes 5′ Strand Resection at a DNA Double-Strand Break

(2008) Ben B. Hopkins et al.   CELL

Mre11 Dimers Coordinate DNA End Bridging and Nuclease Processing in Double-Strand-Break Repair

(2008) R. Scott Williams et al.   CELL

The endless tale of non-homologous end-joining

(2008) Eric Weterings et al.   CELL RESEARCH

Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switching

(2008) Jing H. Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human DNA ligases I and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks

(2008) L. Liang et al.   NUCLEIC ACIDS RESEARCH

Alternative endings

(2008) J. E. Haber   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA