Mitochondrial Dysfunction Impairs Tumor Suppressor p53 Expression/Function

Cancer Abolishes the Tissue Type-Specific Differences in the Phenotype of Energetic Metabolism

(2014) Paloma Acebo et al.   Translational Oncology

Tumorigenic transformation of human breast epithelial cells induced by mitochondrial DNA depletion

(2010) Mariola Kulawiec et al.   CANCER BIOLOGY & THERAPY

In vivo analysis of p53 tumor suppressor function using genetically engineered mouse models

(2010) D. K. Broz et al.   CARCINOGENESIS

Recent Advances in the Genetics of Mitochondrial Encephalopathies

(2010) Elena J. Tucker et al.   Current Neurology and Neuroscience Reports

Mitochondrial ion circuits

(2010) David G. Nicholls   Essays in Biochemistry

Mitochondrial Uncoupling Inhibits p53 Mitochondrial Translocation in TPA-Challenged Skin Epidermal JB6 Cells

(2010) Fei Wang et al.   PLoS One

Pyrimidine biosynthesis links mitochondrial respiration to the p53 pathway

(2010) A. A. Khutornenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantitative Microplate-Based Respirometry with Correction for Oxygen Diffusion

(2009) Akos A. Gerencser et al.   ANALYTICAL CHEMISTRY

Loss of p53 causes mitochondrial DNA depletion and altered mitochondrial reactive oxygen species homeostasis

(2009) Maria A. Lebedeva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The tumor suppressor function of mitochondria: Translation into the clinics

(2009) José M. Cuezva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitochondrial complex I deficiency: from organelle dysfunction to clinical disease

(2009) F. Distelmaier et al.   BRAIN

Mitochondrial NADH-dehydrogenase subunit 3 (ND3) polymorphism (A10398G) and sporadic breast cancer in Poland

(2009) Anna M. Czarnecka et al.   BREAST CANCER RESEARCH AND TREATMENT

Down-regulation of sfrp1 in a mammary epithelial cell line promotes the development of a cd44high/cd24low population which is invasive and resistant to anoikis

(2009) Kelly J Gauger et al.   Cancer Cell International

Suppression of Hypoxia-Inducible Factor 2  Restores p53 Activity via Hdm2 and Reverses Chemoresistance of Renal Carcinoma Cells

(2009) A. M. Roberts et al.   CANCER RESEARCH

Association between common mtDNA variants and all-cause or colorectal cancer mortality

(2009) Evropi Theodoratou et al.   CARCINOGENESIS

Mitochondrial Mutations Contribute to HIF1  Accumulation via Increased Reactive Oxygen Species and Up-regulated Pyruvate Dehydrogenease Kinase 2 in Head and Neck Squamous Cell Carcinoma

(2009) W. Sun et al.   CLINICAL CANCER RESEARCH

Watching the watcher: regulation of p53 by mitochondria

(2009) Aaron K Holley et al.   Future Oncology

The genetic and metabolic signature of oncocytic transformation implicates HIF1α destabilization

(2009) Anna Maria Porcelli et al.   HUMAN MOLECULAR GENETICS

mtDNA G10398A variant in African-American women with breast cancer provides resistance to apoptosis and promotes metastasis in mice

(2009) Mariola Kulawiec et al.   JOURNAL OF HUMAN GENETICS

Synaptic Activity-Mediated Suppression of p53 and Induction of Nuclear Calcium-Regulated Neuroprotective Genes Promote Survival through Inhibition of Mitochondrial Permeability Transition

(2009) D. Lau et al.   JOURNAL OF NEUROSCIENCE

Cytoplasmic functions of the tumour suppressor p53

(2009) Douglas R. Green et al.   NATURE

Akt promotes chemoresistance in human ovarian cancer cells by modulating cisplatin-induced, p53-dependent ubiquitination of FLICE-like inhibitory protein

(2009) M R Abedini et al.   ONCOGENE

Sequence variation in the mitochondrial gene cytochromecoxidase subunit I and prostate cancer in African American men

(2009) Anna M. Ray et al.   PROSTATE

Structural Biology of the Tumor Suppressor p53

(2008) Andreas C. Joerger et al.   Annual Review of Biochemistry

Loss of Complex I due to Mitochondrial DNA Mutations in Renal Oncocytoma

(2008) J. A. Mayr et al.   CLINICAL CANCER RESEARCH

p53: A Guide to Apoptosis

(2008) Erik Meulmeester et al.   CURRENT CANCER DRUG TARGETS

Transcriptional Responses to Estrogen and Progesterone in Mammary Gland Identify Networks Regulating p53 Activity

(2008) Shaolei Lu et al.   ENDOCRINOLOGY

ROS and p53: A versatile partnership

(2008) Bin Liu et al.   FREE RADICAL BIOLOGY AND MEDICINE

CPEB regulation of human cellular senescence, energy metabolism, and p53 mRNA translation

(2008) D. M. Burns et al.   GENES & DEVELOPMENT

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

Mitochondrial complex I inhibition is not required for dopaminergic neuron death induced by rotenone, MPP+, or paraquat

(2008) W.-S. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Investigations of the potential effects of phosphorylation of the MWFE and ESSS subunits on complex I activity and assembly

(2007) N. Yadava et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY