Identification of Integrin β Subunit Mutations That Alter Affinity for Extracellular Matrix Ligand

Regulation of Integrin αIIbβ3 Ligand Binding and Signaling by the Metal Ion Binding Sites in the β I Domain

(2011) Joel Raborn et al.   BIOCHEMISTRY

The final steps of integrin activation: the end game

(2010) Sanford J. Shattil et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Novel S527F Mutation in the Integrin β3 Chain Induces a High Affinity αIIbβ3 Receptor by Hindering Adoption of the Bent Conformation

(2009) Karen Vanhoorelbeke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrin αIIbβ3 Activation in Chinese Hamster Ovary Cells and Platelets Increases Clustering Rather than Affinity

(2009) Thomas A. Bunch   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of the complete integrin αVβ3 ectodomain plus an α/β transmembrane fragment

(2009) Jian-Ping Xiong et al.   JOURNAL OF CELL BIOLOGY

Mechanisms that regulate adaptor binding to  -integrin cytoplasmic tails

(2009) K. R. Legate et al.   JOURNAL OF CELL SCIENCE

The Structure of a Receptor with Two Associating Transmembrane Domains on the Cell Surface: Integrin αIIbβ3

(2009) Jieqing Zhu et al.   MOLECULAR CELL

Key Interactions in Integrin Ectodomain Responsible for Global Conformational Change Detected by Elastic Network Normal-Mode Analysis

(2008) Atsushi Matsumoto et al.   BIOPHYSICAL JOURNAL

Rationally Designed Integrin β3 Mutants Stabilized in the High Affinity Conformation

(2008) Bing-Hao Luo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct Roles of β1 Metal Ion-dependent Adhesion Site (MIDAS), Adjacent to MIDAS (ADMIDAS), and Ligand-associated Metal-binding Site (LIMBS) Cation-binding Sites in Ligand Recognition by Integrin α2β1

(2008) Dimitra Valdramidou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for distinctive recognition of fibrinogen γC peptide by the platelet integrin αIIbβ3

(2008) Timothy A. Springer et al.   JOURNAL OF CELL BIOLOGY

Differences in Regulation of Drosophila and Vertebrate Integrin Affinity by Talin

(2008) Teresa L. Helsten et al.   MOLECULAR BIOLOGY OF THE CELL

Structure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied Forces

(2008) Jianghai Zhu et al.   MOLECULAR CELL

Functional and computational studies of the ligand-associated metal binding site of β3 integrins

(2008) Marta Murcia et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS