Wogonin and Related Natural Flavones Overcome Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Protein Resistance of Tumors by Down-regulation of c-FLIP Protein and Up-regulation of TRAIL Receptor 2 Expression

Wogonin and related natural flavones are inhibitors of CDK9 that induce apoptosis in cancer cells by transcriptional suppression of Mcl-1

(2011) G Polier et al.   Cell Death & Disease

Role of the cyclin-dependent kinase 9-related pathway in mammalian gene expression and human diseases

(2010) Gaetano Romano et al.   CELL CYCLE

Differential regulation of p53 target genes: it's (core promoter) elementary

(2010) N. P. Gomes et al.   GENES & DEVELOPMENT

The Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor

(2010) J. J. Manfredi   GENES & DEVELOPMENT

Phosphorylation of Puma modulates its apoptotic function by regulating protein stability

(2010) M Fricker et al.   Cell Death & Disease

Mdm2-mediated ubiquitylation: p53 and beyond

(2009) J-C Marine et al.   CELL DEATH AND DIFFERENTIATION

Subchronic toxicity and plasma pharmacokinetic studies on wogonin, a natural flavonoid, in Beagle dogs

(2009) Jian Peng et al.   JOURNAL OF ETHNOPHARMACOLOGY

Real-time RT-PCR (TaqMan®) assays for the detection of viruses associated with Rugose wood complex of grapevine

(2008) Fatima Osman et al.   JOURNAL OF VIROLOGICAL METHODS

Wogonin suppresses tumor growth in vivo and VEGF-induced angiogenesis through inhibiting tyrosine phosphorylation of VEGFR2

(2008) Na Lu et al.   LIFE SCIENCES

Toxicological studies of wogonin in experimental animals

(2008) Qi Qi et al.   PHYTOTHERAPY RESEARCH

Cyclin-dependent kinase 9: a key transcriptional regulator and potential drug target in oncology, virology and cardiology

(2008) S WANG et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

FLIP as an Anti-Cancer Therapeutic Target

(2008) Jin Kuk Yang   YONSEI MEDICAL JOURNAL

Anticancer effects of wogonin in both estrogen receptor-positive and -negative human breast cancer cell linesin vitroand in nude mice xenografts

(2007) Heekyoung Chung et al.   INTERNATIONAL JOURNAL OF CANCER