Conversion of 7-Dehydrocholesterol to 7-Ketocholesterol Is Catalyzed by Human Cytochrome P450 7A1 and Occurs by Direct Oxidation without an Epoxide Intermediate

Inhibition of Human Cytochrome P450 3A4 by Cholesterol

(2011) Raku Shinkyo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An oxysterol biomarker for 7-dehydrocholesterol oxidation in cell/mouse models for Smith-Lemli-Opitz syndrome

(2011) Libin Xu et al.   JOURNAL OF LIPID RESEARCH

Cytochrome P450 7A1 Cholesterol 7α-Hydroxylation

(2010) Raku Shinkyo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biological activities of 7-dehydrocholesterol-derived oxysterols: implications for Smith-Lemli-Opitz syndrome

(2010) Zeljka Korade et al.   JOURNAL OF LIPID RESEARCH

Malformation syndromes caused by disorders of cholesterol synthesis

(2010) Forbes D. Porter et al.   JOURNAL OF LIPID RESEARCH

Oxysterols from Free Radical Chain Oxidation of 7-Dehydrocholesterol: Product and Mechanistic Studies

(2010) Libin Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cholesterol Oxidation Products Are Sensitive and Specific Blood-Based Biomarkers for Niemann-Pick C1 Disease

(2010) F. D. Porter et al.   Science Translational Medicine

Rate Constants for Peroxidation of Polyunsaturated Fatty Acids and Sterols in Solution and in Liposomes

(2009) Libin Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cytotoxic effects of oxysterols associated with human diseases: Induction of cell death (apoptosis and/or oncosis), oxidative and inflammatory activities, and phospholipidosis

(2009) Anne Vejux et al.   MOLECULAR ASPECTS OF MEDICINE

Oxysterols and neurodegenerative diseases

(2009) Ingemar Björkhem et al.   MOLECULAR ASPECTS OF MEDICINE

Photodamage Generates 7-keto- and 7-hydroxycholesterol in the Rat Retinaviaa Free Radical-mediated Mechanism

(2009) Ignacio R. Rodriguez et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Side effects of oxysterols: cytotoxicity, oxidation, inflammation, and phospholipidosis

(2008) A. Vejux et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Cholesterol, Reactive Oxygen Species, and the Formation of Biologically Active Mediators

(2008) Robert C. Murphy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Elevated cholesterol precursors other than cholestanol can also be a hallmark for CTX

(2008) M. G. M. de Sain-van der Velden et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Oxysterols: Novel biologic roles for the 21st century

(2007) Norman B. Javitt   STEROIDS