Structural Basis of Drug Binding to CYP46A1, an Enzyme That Controls Cholesterol Turnover in the Brain

Structural Basis of Human CYP51 Inhibition by Antifungal Azoles

(2010) Natallia Strushkevich et al.   JOURNAL OF MOLECULAR BIOLOGY

Cholesterol 24-Hydroxylase: An Enzyme of Cholesterol Turnover in the Brain

(2009) David W. Russell et al.   Annual Review of Biochemistry

Histamine H3 and H4 receptor affinity of branched 3-(1H-imidazol-4-yl)propyl N-alkylcarbamates

(2009) Dorota Łażewska et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Interaction ofMycobacterium tuberculosisCYP130 with Heterocyclic Arylamines

(2009) Larissa M. Podust et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The antifungal drug voriconazole is an efficient inhibitor of brain cholesterol 24S-hydroxylase in vitro and in vivo

(2009) Marjan Shafaati et al.   JOURNAL OF LIPID RESEARCH

Adeno-associated Virus Gene Therapy With Cholesterol 24-Hydroxylase Reduces the Amyloid Pathology Before or After the Onset of Amyloid Plaques in Mouse Models of Alzheimer's Disease

(2009) Eloise Hudry et al.   MOLECULAR THERAPY

Reduction of cholesterol synthesis in the mouse brain does not affect amyloid formation in Alzheimer's disease, but does extend lifespan

(2009) R. W. Halford et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New paradigm for macromolecular crystallography experiments at SSRL: automated crystal screening and remote data collection

(2008) S. Michael Soltis et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

How Do Azoles Inhibit Cytochrome P450 Enzymes? A Density Functional Study†

(2008) Philip R. Balding et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brain

(2008) N. Mast et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA