Stable α-Synuclein Oligomers Strongly Inhibit Chaperone Activity of the Hsp70 System by Weak Interactions with J-domain Co-chaperones

Protein homeostasis and aging: The importance of exquisite quality control

(2010) Hiroshi Koga et al.   AGEING RESEARCH REVIEWS

Meta-analysis of heat- and chemically upregulated chaperone genes in plant and human cells

(2010) Andrija Finka et al.   CELL STRESS & CHAPERONES

DnaK/DnaJ/GrpE of Hsp70 system have differing effects on α-synuclein fibrillation involved in Parkinson's disease

(2010) Atta Ahmad   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

A DNAJB Chaperone Subfamily with HDAC-Dependent Activities Suppresses Toxic Protein Aggregation

(2010) Jurre Hageman et al.   MOLECULAR CELL

The kinetic parameters and energy cost of the Hsp70 chaperone as a polypeptide unfoldase

(2010) Sandeep K Sharma et al.   Nature Chemical Biology

Disaggregating Chaperones: An Unfolding Story

(2009) Sandeep Sharma et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Brain-Permeable Small-Molecule Inhibitors of Hsp90 Prevent  -Synuclein Oligomer Formation and Rescue  -Synuclein-Induced Toxicity

(2009) P. Putcha et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Structural Properties of Pore-Forming Oligomers of α-Synuclein

(2009) Hai-Young Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Converging concepts of protein folding in vitro and in vivo

(2009) F Ulrich Hartl et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Alterations in lysosomal and proteasomal markers in Parkinson's disease: Relationship to alpha-synuclein inclusions

(2009) Yaping Chu et al.   NEUROBIOLOGY OF DISEASE

Polypeptide transfer from Hsp40 to Hsp70 molecular chaperones

(2009) Daniel W. Summers et al.   TRENDS IN BIOCHEMICAL SCIENCES

Hsp104, Hsp70 and Hsp40 interplay regulates formation, growth and elimination of Sup35 prions

(2008) James Shorter et al.   EMBO JOURNAL

α-Synuclein Protofibrils Inhibit 26 S Proteasome-mediated Protein Degradation

(2008) Nan-Yan Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hsp104 antagonizes α-synuclein aggregation and reduces dopaminergic degeneration in a rat model of Parkinson disease

(2008) Christophe Lo Bianco et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular Basis for Regulation of the Heat Shock Transcription Factor σ32 by the DnaK and DnaJ Chaperones

(2008) Fernanda Rodriguez et al.   MOLECULAR CELL

Adapting Proteostasis for Disease Intervention

(2008) William E. Balch et al.   SCIENCE

Non-steroidal anti-inflammatory drugs have potent anti-fibrillogenic and fibril-destabilizing effects for α-synuclein fibrils in vitro

(2007) Mie Hirohata et al.   NEUROPHARMACOLOGY

The solubility of α-synuclein in multiple system atrophy differs from that of dementia with Lewy bodies and Parkinson's disease

(2003) Bruce C. V. Campbell et al.   JOURNAL OF NEUROCHEMISTRY