Article
Engineering, Mechanical
Matheus Rabelo, Hasnain Yousuf, Yewon Cha, Vinh-Ai Dao, Youngkuk Kim, Duy Phong Pham, Junsin Yi
Summary: Experimental and numerical analysis showed that power reduction in silicon photovoltaic modules occurs faster in acidic environments than in pure water, with over 60% power loss in all environments after 144 hours. Particularly, a high acetic acid concentration of 20 wt% led to a rapid power loss of over 40% after just 48 hours. The corrosion of rear aluminum around the silver contact is identified as the main cause of device power losses, which can be efficiently prevented by a polymer (EPDM) without increasing production costs.
ENGINEERING FAILURE ANALYSIS
(2022)
Article
Biochemistry & Molecular Biology
Hui Chen, Bo Jiang, Chunyang Zou, Zhichao Lou, Junlong Song, Wenjuan Wu, Yongcan Jin
Summary: In this study, the interaction between lignin and cellulase was investigated using a carbohydrate-binding module (CBM) functionalized atomic force microscope tip. The results showed that sulfonated lignin (SL) had the strongest adhesion force to CBM, while other lignin samples had weaker adhesion forces. It was found that the primary mechanism by which SL promoted hydrolysis was by reducing the nonproductive adsorption of substrate lignin onto cellulase. The study also proposed a competitive adsorption mechanism to explain the effective promotion of enzymatic hydrolysis by SL in lignin-containing substrates.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biotechnology & Applied Microbiology
Xinguo Lu, Fang Liu, Qiumai Miao, Ping Liu, Yan Gao, Keren He
Summary: Our study aimed to reveal functional overlapping patterns in gene modules to elucidate regulatory relationships between overlapping genes and communities, as well as explore cancer formation and progression. We analyzed six cancer datasets and identified three types of gene functional modules for each cancer, with our method outperforming others in terms of identifying distinguishing communities and survival prognostics for patients. In conclusion, overlapping genes play a crucial role in constructing comprehensive carcinogenesis by establishing communication bridges between different specific functional groups.
Article
Biochemistry & Molecular Biology
Yajing Liu, Jian Wang, Chengling Bao, Bing Dong, Yunhe Cao
Summary: This study investigated a novel endo-xylanase with potential applications in biomass hydrolysis. It was found that the enzyme showed high activity in degrading xylan from various biomass sources and synergized with cellulase to improve hydrolysis efficiency. The study demonstrated the potential of this enzyme in biofuel production.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Agricultural Engineering
Xiaoxue Zhao, Caoxing Huang, Wenqian Lin, Bin Bian, Chenhuan Lai, Zhe Ling, Qiang Yong
Summary: This study investigated the adsorption mechanism and structure-activity relationship between lignin and different cellulase domains using fluorescence spectroscopy and SDS-PAGE. It was found that endo-cellulase 6B had a higher affinity to lignin fractions, which was positively correlated to molecular weight. The adsorption between lignin fractions and endo-cellulase 6B was mainly driven by van der Waals and electrostatic forces, while hydrophobic force drove the adsorption of lignin fractions to CBM4A. The results demonstrated the critical role of lignin's structure in its adsorption with various cellulase domains.
BIORESOURCE TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Xuanwei Mei, Yuying Zhang, Guanchen Liu, Jingjing Shen, Jin Han, Changhu Xue, Hang Xiao, Yaoguang Chang
Summary: In this study, a previously unknown domain with a predicted 13-sandwich fold structure was discovered in a potential GH86 porphyranase and successfully expressed in a CBM protein (FvCBM99). FvCBM99 specifically binds to porphyran tetrasaccharide and has potential applications in the in situ visualization of porphyran.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Thermodynamics
Lin Liu, Xiangning Meng, Zhuang Miao, Sen Zhou
Summary: The stability and power generation of a conventional cube-type thermoelectric module were analyzed. Stress concentration in the copper electrodes of the cube-type module was identified. The redesign of the TE legs into cylinder shape reduced stress concentration. Furthermore, a truncated cone-type TE module with a smaller cold end area was designed, resulting in optimized application stability and power generation.
CASE STUDIES IN THERMAL ENGINEERING
(2022)
Article
Mathematics
Daniele Boffi, Lucia Gastaldi
Summary: This paper considers the linearized version of a system of partial differential equations arising from a fluid-structure interaction model, and proves the existence and uniqueness of the solution under natural regularity assumptions.
JOURNAL OF DIFFERENTIAL EQUATIONS
(2021)
Article
Biochemical Research Methods
Xueyan Liu, Yong Xu, Ran Wang, Sheng Liu, Jun Wang, YongLun Luo, Kwong-Sak Leung, Lixin Cheng
Summary: MoonFinder v2.0 is an algorithm dedicated to predicting human mlncRNAs, providing a comprehensive framework and a moonlighting coefficient for assessing their cellular functions. Studies have shown that mlncRNAs exhibit specific expression characteristics in sepsis and tend to be mutually exclusive in terms of coexpression compared to other lncRNAs.
BRIEFINGS IN BIOINFORMATICS
(2021)
Article
Computer Science, Interdisciplinary Applications
Muzaffer Akbay, Craig Schroeder, Tamar Shinar
Summary: The paper presents a boundary pressure projection method to alleviate the incompatibility while addressing the incompressibility dilemma. This method projects incompatible velocities from the structure solver to be compatible and computes constant pressure modes for the Dirichlet regions.
JOURNAL OF COMPUTATIONAL PHYSICS
(2021)
Article
Multidisciplinary Sciences
Cristina Cecchetti, Jannik Strauss, Claudia Stohrer, Claire Naylor, Edward Pryor, Jeanette Hobbs, Simon Tanley, Adrian Goldman, Bernadette Byrne
Summary: Researchers have developed a screening method to aid in the high-throughput identification of beneficial lipids for membrane proteins, successfully identifying stabilizing lipids for three different membrane proteins. This novel tool has potential applications in membrane protein research and will be commercially available in the future.
Article
Biophysics
Lijuan Wang, Yiya Wang, Siyuan Chang, Zhen Gao, Jiangfeng Ma, Bin Wu, Bingfang He, Ping Wei
Summary: The extracellular thermostable xylanase (XynNTU) from Paenibacillus campinasensis NTU-11 displayed high thermal stability and specific activity, with truncated mutants showing similar optimal conditions. The carbohydrate-binding module (CBM6) was crucial for enzyme-substrate binding and hydrolysis, highlighting the potential industrial applications of XynNTU and its mutants.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Agriculture, Multidisciplinary
Xuanwei Mei, Yuying Zhang, Xiaoxiao Jiang, Guanchen Liu, Jingjing Shen, Changhu Xue, Hang Xiao, Yaoguang Chang
Summary: A novel agarose-binding CBM, WfCBM101, was discovered and characterized in this study. This research provides important insights into the study of agarose.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Agriculture, Multidisciplinary
Xuanwei Mei, Yaoguang Chang, Jingjing Shen, Yuying Zhang, Jin Han, Changhu Xue
Summary: In this study, an unknown function module Cgk16A-CBM92 from Cgk16A was cloned and expressed, and it was found to specifically bind to carrageenan. This discovery provides a potential tool for the in situ investigation of carrageenan.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Review
Biochemistry & Molecular Biology
Ning Zhang, Zihao Chen, Dingdong Liu, Hewen Jiang, Zong-Kang Zhang, Aiping Lu, Bao-Ting Zhang, Yuanyuan Yu, Ge Zhang
Summary: Aptamers show promise as therapeutic and diagnostic agents for various diseases due to their high affinity and specificity. Structural studies and modification strategies are crucial for understanding and optimizing the interactions between aptamers and target proteins. Challenges in resolving aptamer-protein complex structures still exist, but advancements in methodologies could facilitate the development of aptamer-based therapeutics.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Cell Biology
Yoshihiro Kobashigawa, Shinjiro Amano, Mariko Yokogawa, Hiroyuki Kumeta, Hiroshi Morioka, Masayori Inouye, Joseph Schlessinger, Fuyuhiko Inagaki
Article
Multidisciplinary Sciences
Tomohide Saio, Kenji Ogura, Hiroyuki Kumeta, Yoshihiro Kobashigawa, Kazumi Shimizu, Masashi Yokochi, Kota Kodama, Hiroto Yamaguchi, Hideki Tsujishita, Fuyuhiko Inagaki
SCIENTIFIC REPORTS
(2015)
Article
Biochemistry & Molecular Biology
Mizue Imai, Tomohide Saio, Hiroyuki Kumeta, Takeshi Uchida, Fuyuhiko Inagaki, Koichiro Ishimori
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2016)
Article
Cell Biology
Yoshihiro Kobashigawa, Shinjiro Amano, Kaito Yoza, Rika Himeno, Shun Amemiya, Hiroshi Morioka, Mariko Yokogawa, Hiroyuki Kumeta, Joseph Schlessinger, Fuyuhiko Inagaki
Article
Cell Biology
Kaito Yoza, Rika Himeno, Shinjiro Amano, Yoshihiro Kobashigawa, Shun Amemiya, Natsuki Fukuda, Hiroyuki Kumeta, Hiroshi Morioka, Fuyuhiko Inagaki
Article
Cell Biology
Akinori Yamasaki, Yasunori Watanabe, Wakana Adachi, Kuninori Suzuki, Kazuaki Matoba, Hiromi Kirisako, Hiroyuki Kumeta, Hitoshi Nakatogawa, Yoshinori Ohsumi, Fuyuhiko Inagaki, Nobuo N. Noda
Article
Biochemistry & Molecular Biology
Natsuki Fukuda, Kentaro Noi, Lidong Weng, Yoshihiro Kobashigawa, Hiromi Miyazaki, Yukari Wakeyama, Michiyo Takaki, Yusuke Nakahara, Yuka Tatsuno, Makiyo Uchida-Kamekura, Yoshiaki Suwa, Takashi Sato, Naoki Ichikawa-Tomikawa, Motoyoshi Nomizu, Yukio Fujiwara, Fumina Ohsaka, Takashi Saito, Katsumi Maenaka, Hiroyuki Kumeta, Shoko Shinya, Chojiro Kojima, Teru Ogura, Hiroshi Morioka
Article
Biochemistry & Molecular Biology
Soichiro Kawagoe, Hiroshi Nakagawa, Hiroyuki Kumeta, Koichiro Ishimori, Tomohide Saio
JOURNAL OF BIOLOGICAL CHEMISTRY
(2018)
Article
Biochemistry & Molecular Biology
Hiroyuki Kumeta, Kenji Ogura, Yoshiyuki Nishimiya, Ai Miura, Fuyuhiko Inagaki, Sakae Tsuda
JOURNAL OF BIOMOLECULAR NMR
(2013)
Article
Biochemistry & Molecular Biology
Hiroyuki Kumeta, Hiromi Sakakibara, Yoshiaki Enokizono, Kenji Ogura, Masataka Horiuchi, Misako Matsumoto, Tsukasa Seya, Fuyuhiko Inagaki
JOURNAL OF BIOMOLECULAR NMR
(2014)
Article
Biochemical Research Methods
Neil J. Stewart, Hiroyuki Kumeta, Mitsushi Tomohiro, Takuya Hashimoto, Noriyuki Hatae, Shingo Matsumoto
JOURNAL OF MAGNETIC RESONANCE
(2018)
Article
Multidisciplinary Sciences
Mariko Yokogawa, Takashi Tsushima, Nobuo N. Noda, Hiroyuki Kumeta, Yoshiaki Enokizono, Kazuo Yamashita, Daron M. Standley, Osamu Takeuchi, Shizuo Akira, Fuyuhiko Inagaki
SCIENTIFIC REPORTS
(2016)
Article
Multidisciplinary Sciences
Hiroyuki Kumeta, Haruka Nakayama, Kenji Ogura
SCIENTIFIC REPORTS
(2017)
Article
Food Science & Technology
Yukiko Horie, Hideyuki Nemote, Jin Fujita, Shigeo Ikegawa, Yasuhiro Kumaki, Yuki Ohnishi, Hiroyuki Kumeta, Makoto Demura, Tomoyasu Aizawa
JOURNAL OF THE JAPANESE SOCIETY FOR FOOD SCIENCE AND TECHNOLOGY-NIPPON SHOKUHIN KAGAKU KOGAKU KAISHI
(2019)
Article
Biochemistry & Molecular Biology
Zihao Song, Yuki Ohnishi, Seiji Osada, Li Gan, Jiaxi Jiang, Zhiyan Hu, Hiroyuki Kumeta, Yasuhiro Kumaki, Yuki Yokoi, Kiminori Nakamura, Tokiyoshi Ayabe, Kazuo Yamauchi, Tomoyasu Aizawa
Summary: NMR-based metabolomics is widely used in research to identify biomarkers and investigate the pathogenesis of diseases. This study applied a low-field NMR spectrometer to analyze the metabolic profile of ulcerative colitis model mice and compared it with high-field NMR. The results showed high comparability and accurate quantification of metabolites using the low-field NMR.