Hsp70 and Hsp40 Functionally Interact with Soluble Mutant Huntingtin Oligomers in a Classic ATP-dependent Reaction Cycle

Mutant Huntingtin Fragments Form Oligomers in a Polyglutamine Length-dependent Mannerin Vitroandin Vivo

(2010) Justin Legleiter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acute Polyglutamine Expression in Inducible Mouse Model Unravels Ubiquitin/Proteasome System Impairment and Permanent Recovery Attributable to Aggregate Formation

(2010) Z. Ortega et al.   JOURNAL OF NEUROSCIENCE

A DNAJB Chaperone Subfamily with HDAC-Dependent Activities Suppresses Toxic Protein Aggregation

(2010) Jurre Hageman et al.   MOLECULAR CELL

Chaperone proteostasis in Parkinson's disease: stabilization of the Hsp70/α-synuclein complex by Hip

(2009) Cintia Roodveldt et al.   EMBO JOURNAL

Monoclonal Antibodies Recognize Distinct Conformational Epitopes Formed by Polyglutamine in a Mutant Huntingtin Fragment

(2009) Justin Legleiter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of Hsp70 Exacerbates Pathogenesis But Not Levels of Fibrillar Aggregates in a Mouse Model of Huntington's Disease

(2009) J. L. Wacker et al.   JOURNAL OF NEUROSCIENCE

Secondary Structure of Huntingtin Amino-Terminal Region

(2009) Mee Whi Kim et al.   STRUCTURE

Polyglutamine Dances the Conformational Cha-Cha-Cha

(2009) Jason Miller et al.   STRUCTURE

Single Neuron Ubiquitin-Proteasome Dynamics Accompanying Inclusion Body Formation in Huntington Disease

(2008) Siddhartha Mitra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Classification of Toxic Amyloid Oligomers

(2008) Charles G. Glabe   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel HSP90 chaperone complex regulates intracellular vesicle transport

(2008) G. P. Lotz et al.   JOURNAL OF CELL SCIENCE

Amyloid Oligomer Conformation in a Group of Natively Folded Proteins

(2008) Yuji Yoshiike et al.   PLoS One

Adapting Proteostasis for Disease Intervention

(2008) William E. Balch et al.   SCIENCE