Insulin-like Growth Factor-1 (IGF-1)-induced Processing of Amyloid-β Precursor Protein (APP) and APP-like Protein 2 Is Mediated by Different Metalloproteinases

γ-secretase processing of APLP1 leads to the production of a p3-like peptide that does not aggregate and is not toxic to neurons

(2009) Aedín M. Minogue et al.   BRAIN RESEARCH

Amyloid precursor protein and its homologues: a family of proteolysis-dependent receptors

(2009) Kristin T. Jacobsen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Subcellular localization and dimerization of APLP1 are strikingly different from APP and APLP2

(2009) D. Kaden et al.   JOURNAL OF CELL SCIENCE

ADAMs 10 and 17 Represent Differentially Regulated Components of a General Shedding Machinery for Membrane Proteins Such as Transforming Growth Factor α, L-Selectin, and Tumor Necrosis Factor α

(2009) Sylvain M. Le Gall et al.   MOLECULAR BIOLOGY OF THE CELL

APP binds DR6 to trigger axon pruning and neuron death via distinct caspases

(2009) Anatoly Nikolaev et al.   NATURE

Part-Time α-Secretases: The Functional Biology of ADAM 9, 10 and 17

(2008) Miriam Deuss et al.   Current Alzheimer Research

Aldose Reductase Regulates High Glucose-Induced Ectodomain Shedding of Tumor Necrosis Factor (TNF)-α via Protein Kinase C-δ and TNF-α Converting Enzyme in Vascular Smooth Muscle Cells

(2008) Aramati B. M. Reddy et al.   ENDOCRINOLOGY

Homophilic Interactions of the Amyloid Precursor Protein (APP) Ectodomain Are Regulated by the Loop Region and Affect β-Secretase Cleavage of APP

(2008) Daniela Kaden et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of the Alzheimer's disease amyloid precursor protein (APP) and its homologue APLP2 as essential modulators of glucose and insulin homeostasis and growth

(2008) BE Needham et al.   JOURNAL OF PATHOLOGY

PI3-K- and PKC-dependent up-regulation of APP processing enzymes by retinoic acid

(2007) Sofia Holback et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS