Role of Epithelial Sodium Channels and Their Regulators in Hypertension

A mutation of the epithelial sodium channel associated with atypical cystic fibrosis increases channel open probability and reduces Na+self inhibition

(2010) Robert Rauh et al.   JOURNAL OF PHYSIOLOGY-LONDON

mTOR Complex-2 Activates ENaC by Phosphorylating SGK1

(2010) M. Lu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The physiological impact of the serum and glucocorticoid-inducible kinase SGK1

(2009) Florian Lang et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Cnksr3 is a direct mineralocorticoid receptor target gene and plays a key role in the regulation of the epithelial sodium channel

(2009) Tim Ziera et al.   FASEB JOURNAL

Mutations in the amiloride-sensitive epithelial sodium channel in patients with cystic fibrosis-like disease

(2009) Abul Kalam Azad et al.   HUMAN MUTATION

Novel Determinants of Epithelial Sodium Channel Gating within Extracellular Thumb Domains

(2009) Ahmad B. Maarouf et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extracellular Chloride Regulates the Epithelial Sodium Channel

(2009) Daniel M. Collier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ENaC at the Cutting Edge: Regulation of Epithelial Sodium Channels by Proteases

(2009) Thomas R. Kleyman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aldosterone mediates activation of the thiazide-sensitive Na-Cl cotransporter through an SGK1 and WNK4 signaling pathway

(2009) David J. Rozansky et al.   JOURNAL OF CLINICAL INVESTIGATION

Epithelial sodium channel regulated by differential composition of a signaling complex

(2009) R. Soundararajan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of the Epithelial Sodium Channel (ENaC) by Serine Proteases

(2008) Bernard C. Rossier et al.   Annual Review of Physiology

Genetic Analysis of Rwandan Patients With Cystic Fibrosis-Like Symptoms

(2008) Léon Mutesa et al.   CHEST

Plasmin Activates Epithelial Na+Channels by Cleaving the γ Subunit

(2008) Christopher J. Passero et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of ENaC Regulation and Clinical Implications

(2008) V. Bhalla et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Plasmin in Nephrotic Urine Activates the Epithelial Sodium Channel

(2008) P. Svenningsen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Lack of Association of Functional Variants in Alpha-ENaC Gene and Essential Hypertension in Two Ethnic Groups in China

(2008) Xiao-feng Wang et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Molecular Physiology of the WNK Kinases

(2007) Kristopher T. Kahle et al.   Annual Review of Physiology