MAP/ERK Kinase Kinase 1 (MEKK1) Mediates Transcriptional Repression by Interacting with Polycystic Kidney Disease-1 (PKD1) Promoter-bound p53 Tumor Suppressor Protein

Mechanisms of p53-mediated repression of the human polycystic kidney disease-1 promoter

(2010) Diederik van Bodegom et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Polycystins and Primary Cilia: Primers for Cell Cycle Progression

(2009) Jing Zhou   Annual Review of Physiology

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Modes of p53 Regulation

(2009) Jan-Philipp Kruse et al.   CELL

Regulation of p53 - insights into a complex process

(2009) Karen A Boehme et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Advances in the pathogenesis and treatment of polycystic kidney disease

(2009) Vishal Patel et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Cdc42 is an antihypertrophic molecular switch in the mouse heart

(2009) Marjorie Maillet et al.   JOURNAL OF CLINICAL INVESTIGATION

2008 Homer W. Smith Award: Insights into the Pathogenesis of Polycystic Kidney Disease from Gene Discovery

(2009) P. C. Harris   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The diversity of PKD1 alleles: implications for disease pathogenesis and genetic counseling

(2009) Richard N. Sandford   KIDNEY INTERNATIONAL

Autosomal dominant polycystic kidney disease: the last 3 years

(2009) Vicente E. Torres et al.   KIDNEY INTERNATIONAL

c-Jun-NH2 terminal kinase (JNK)-mediates AP-1 activation by thioredoxin: phosphorylation of cJun, JunB, and Fra-1

(2009) Kumuda C. Das et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Identification of a Novel Amino Acid Response Pathway Triggering ATF2 Phosphorylation in Mammals

(2009) C. Chaveroux et al.   MOLECULAR AND CELLULAR BIOLOGY

Elucidation of the signaling network of COX-2 induction in sheared chondrocytes: COX-2 is induced via a Rac/MEKK1/MKK7/JNK2/c-Jun-C/EBPβ-dependent pathway

(2008) Zachary R. Healy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Polycystic Kidney Disease

(2008) Peter C. Harris et al.   Annual Review of Medicine

Simulation of crosstalk between small GTPase RhoA and EGFR-ERK signaling pathway via MEKK1

(2008) Hu Li et al.   BIOINFORMATICS

The complexity of mitogen-activated protein kinases (MAPKs) made simple

(2008) M. Krishna et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A tumor necrosis factor-α–mediated pathway promoting autosomal dominant polycystic kidney disease

(2008) Xiaogang Li et al.   NATURE MEDICINE

Autosomal Dominant Polycystic Kidney Disease

(2008) Jared J. Grantham   NEW ENGLAND JOURNAL OF MEDICINE

Alpha-lipoic acid inhibits TNF-α induced NF-κB activation through blocking of MEKK1–MKK4–IKK signaling cascades

(2007) Chang-Keun Lee et al.   INTERNATIONAL IMMUNOPHARMACOLOGY