Increased E4 Activity in Mice Leads to Ubiquitin-containing Aggregates and Degeneration of Hypothalamic Neurons Resulting in Obesity

Autophagy Inhibition Compromises Degradation of Ubiquitin-Proteasome Pathway Substrates

(2009) Viktor I. Korolchuk et al.   MOLECULAR CELL

Common and specific roles of the related CDK inhibitors p27 and p57 revealed by a knock-in mouse model

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Obesity and vulnerability of the CNS

(2008) Annadora J. Bruce-Keller et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Ref(2)P, theDrosophila melanogasterhomologue of mammalian p62, is required for the formation of protein aggregates in adult brain

(2008) Ioannis P. Nezis et al.   JOURNAL OF CELL BIOLOGY

Impaired ubiquitin–proteasome system activity in the synapses of Huntington's disease mice

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Relevance of animal models to human eating disorders and obesity

(2008) Regina C. Casper et al.   PSYCHOPHARMACOLOGY

Aβ inhibits the proteasome and enhances amyloid and tau accumulation

(2007) Bertrand P. Tseng et al.   NEUROBIOLOGY OF AGING