Crowded Cell-like Environment Accelerates the Nucleation Step of Amyloidogenic Protein Misfolding

Macromolecular Crowding and Confinement: Biochemical, Biophysical, and Potential Physiological Consequences

(2008) Huan-Xiang Zhou et al.   Annual Review of Biophysics

Amyloidogenesis in its biological environment: challenging a fundamental issue in protein misfolding diseases

(2008) Vittorio Bellotti et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The two faces of protein misfolding: gain- and loss-of-function in neurodegenerative diseases

(2008) Konstanze F Winklhofer et al.   EMBO JOURNAL

Macromolecular Crowding Compacts Unfolded Apoflavodoxin and Causes Severe Aggregation of the Off-pathway Intermediate during Apoflavodoxin Folding

(2008) Ruchira Engel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of Truncated Forms of Abnormal Prion Protein in Creutzfeldt-Jakob Disease

(2008) Silvio Notari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conformational Stability of PrP Amyloid Fibrils Controls Their Smallest Possible Fragment Size

(2008) Ying Sun et al.   JOURNAL OF MOLECULAR BIOLOGY

Misfolded proteins partition between two distinct quality control compartments

(2008) Daniel Kaganovich et al.   NATURE

A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo

(2008) Scott A Yuzwa et al.   Nature Chemical Biology

Crowded, cell-like environment induces shape changes in aspherical protein

(2008) D. Homouz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systematic analysis of nucleation-dependent polymerization reveals new insights into the mechanism of amyloid self-assembly

(2008) Wei-Feng Xue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of prion protein assembly into amyloid

(2008) J. Stohr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Initiation and elongation in fibrillation of ALS-linked superoxide dismutase

(2008) M. Chattopadhyay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA