Binding and Orientation of Tricyclic Antidepressants within the Central Substrate Site of the Human Serotonin Transporter

The Two Enantiomers of Citalopram Bind to the Human Serotonin Transporter in Reversed Orientations

(2010) Heidi Koldsø et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Location of the Antidepressant Binding Site in the Serotonin Transporter

(2009) Jacob Andersen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Control of Ion Selectivity in LeuT: Two Na+ Binding Sites with Two Different Mechanisms

(2008) Sergei Y. Noskov et al.   JOURNAL OF MOLECULAR BIOLOGY

Antidepressants Targeting the Serotonin Reuptake Transporter Act via a Competitive Mechanism

(2008) S. Apparsundaram et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Binding of Serotonin to the Human Serotonin Transporter. Molecular Modeling and Experimental Validation

(2008) Leyla Celik et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Mechanism of a Neurotransmitter:Sodium Symporter—Inward Release of Na+ and Substrate Is Triggered by Substrate in a Second Binding Site

(2008) Lei Shi et al.   MOLECULAR CELL

The binding sites for cocaine and dopamine in the dopamine transporter overlap

(2008) Thijs Beuming et al.   NATURE NEUROSCIENCE

Mechanism for alternating access in neurotransmitter transporters

(2008) L. R. Forrest et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Competitive Inhibitor Traps LeuT in an Open-to-Out Conformation

(2008) S. K. Singh et al.   SCIENCE

Substrate Binding and Formation of an Occluded State in the Leucine Transporter

(2007) Leyla Celik et al.   BIOPHYSICAL JOURNAL