Identification of the Penta-EF-hand Protein ALG-2 as a Ca2+-dependent Interactor of Mucolipin-1

Mucolipidosis type IV: The importance of functional lysosomes for efficient autophagy

(2014) Silvia Vergarajauregui et al.   Autophagy

Penta-EF-hand protein ALG-2 functions as a Ca2+-dependent adaptor that bridges Alix and TSG101

(2009) Mayumi Okumura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The mechanism of Ca2+-dependent recognition of Alix by ALG-2: insights from X-ray crystal structures

(2009) Hironori Suzuki et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Chaperone-mediated autophagy is defective in mucolipidosis type IV

(2009) Bhuvarahamurthy Venugopal et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mucolipin 1 channel activity is regulated by protein kinase A-mediated phosphorylation

(2008) Silvia Vergarajauregui et al.   BIOCHEMICAL JOURNAL

Motor Deficit in a Drosophila Model of Mucolipidosis Type IV due to Defective Clearance of Apoptotic Cells

(2008) Kartik Venkatachalam et al.   CELL

Autophagic dysfunction in mucolipidosis type IV patients

(2008) Silvia Vergarajauregui et al.   HUMAN MOLECULAR GENETICS

Identification of Alix-type and Non-Alix-type ALG-2-binding Sites in Human Phospholipid Scramblase 3

(2008) Hideki Shibata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane traffic and turnover in TRP-ML1–deficient cells: a revised model for mucolipidosis type IV pathogenesis

(2008) Mark T. Miedel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel

(2008) Xian-Ping Dong et al.   NATURE

Structural Basis for Ca2+-Dependent Formation of ALG-2/Alix Peptide Complex: Ca2+/EF3-Driven Arginine Switch Mechanism

(2008) Hironori Suzuki et al.   STRUCTURE