The Chaperones Hsp90 and Cdc37 Mediate the Maturation and Stabilization of Protein Kinase C through a Conserved PXXP Motif in the C-terminal Tail

The heat shock protein antagonist 17-AAG potentiates the activity of enzastaurin against malignant human glioma cells

(2008) Esther P. Jane et al.   CANCER LETTERS

Prediction of Cancer Driver Mutations in Protein Kinases

(2008) A. Torkamani et al.   CANCER RESEARCH

The Life and Death of Protein Kinase C

(2008) Christine Gould et al.   CURRENT DRUG TARGETS

Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling

(2008) Tsuneo Ikenoue et al.   EMBO JOURNAL

The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C

(2008) Valeria Facchinetti et al.   EMBO JOURNAL

PKC alpha protein but not kinase activity is critical for glioma cell proliferation and survival

(2008) Angus J. Cameron et al.   INTERNATIONAL JOURNAL OF CANCER

A novel Hsp90 inhibitor to disrupt Hsp90/Cdc37 complex against pancreatic cancer cells

(2008) T. Zhang et al.   MOLECULAR CANCER THERAPEUTICS

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

L347P PINK1 mutant that fails to bind to Hsp90/Cdc37 chaperones is rapidly degraded in a proteasome-dependent manner

(2008) Yasuhiro Moriwaki et al.   NEUROSCIENCE RESEARCH