Vps4 disassembles an ESCRT-III filament by global unfolding and processive translocation

Mechanistic insights into the recycling machine of the SNARE complex

(2015) Minglei Zhao et al.   NATURE

Structural analysis and modeling reveals new mechanisms governing ESCRT-III spiral filament assembly

(2014) Qing-Tao Shen et al.   JOURNAL OF CELL BIOLOGY

Polarized release of T-cell-receptor-enriched microvesicles at the immunological synapse

(2014) Kaushik Choudhuri et al.   NATURE

ESCRT Machinery Is Required for Plasma Membrane Repair

(2014) A. J. Jimenez et al.   SCIENCE

Structure of cellular ESCRT-III spirals and their relationship to HIV budding

(2014) Anil G Cashikar et al.   eLife

Virus Budding and the ESCRT Pathway

(2013) Jörg Votteler et al.   Cell Host & Microbe

The Oligomeric State of the Active Vps4 AAA ATPase

(2013) Nicole Monroe et al.   JOURNAL OF MOLECULAR BIOLOGY

Knowing when to cut and run: mechanisms that control cytokinetic abscission

(2013) Monica Agromayor et al.   TRENDS IN CELL BIOLOGY

The Endosomal Sorting Complex ESCRT-II Mediates the Assembly and Architecture of ESCRT-III Helices

(2012) William Mike Henne et al.   CELL

Multivesicular Body Morphogenesis

(2011) Phyllis I. Hanson et al.   Annual Review of Cell and Developmental Biology

Structure and function of the membrane deformation AAA ATPase Vps4

(2011) Christopher P. Hill et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

ClpXP, an ATP-powered unfolding and protein-degradation machine

(2011) Tania A. Baker et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

ClpX(P) Generates Mechanical Force to Unfold and Translocate Its Protein Substrates

(2011) Rodrigo A. Maillard et al.   CELL

Cortical Constriction During Abscission Involves Helices of ESCRT-III-Dependent Filaments

(2011) J. Guizetti et al.   SCIENCE

How Ubiquitin Functions with ESCRTs

(2011) S. Brookhart Shields et al.   TRAFFIC

Coordination of Substrate Binding and ATP Hydrolysis in Vps4-Mediated ESCRT-III Disassembly

(2010) Brian A. Davies et al.   MOLECULAR BIOLOGY OF THE CELL

The AAA+ ClpX machine unfolds a keystone subunit to remodel the Mu transpososome

(2010) A. H. Abdelhakim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structures of Asymmetric ClpX Hexamers Reveal Nucleotide-Dependent Motions in a AAA+ Protein-Unfolding Machine

(2009) Steven E. Glynn et al.   CELL

Polypeptide Translocation by the AAA+ ClpXP Protease Machine

(2009) Sarah R. Barkow et al.   CHEMISTRY & BIOLOGY

Structural Basis of Ist1 Function and Ist1–Did2 Interaction in the Multivesicular Body Pathway and Cytokinesis

(2009) Junyu Xiao et al.   MOLECULAR BIOLOGY OF THE CELL

Membrane scission by the ESCRT-III complex

(2009) Thomas Wollert et al.   NATURE

Structural basis for ESCRT-III protein autoinhibition

(2009) Monika Bajorek et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Three-Dimensional Structure of AAA ATPase Vps4: Advancing Structural Insights into the Mechanisms of Endosomal Sorting and Enveloped Virus Budding

(2009) Michael John Landsberg et al.   STRUCTURE

ESCRT-III Family Members Stimulate Vps4 ATPase Activity Directly or via Vta1

(2008) Ishara F. Azmi et al.   DEVELOPMENTAL CELL

MIT Domainia

(2008) James H. Hurley et al.   DEVELOPMENTAL CELL

Two Distinct Modes of ESCRT-III Recognition Are Required for VPS4 Functions in Lysosomal Protein Targeting and HIV-1 Budding

(2008) Collin Kieffer et al.   DEVELOPMENTAL CELL

Plasma membrane deformation by circular arrays of ESCRT-III protein filaments

(2008) Phyllis I. Hanson et al.   JOURNAL OF CELL BIOLOGY

Biochemical and Structural Studies of Yeast Vps4 Oligomerization

(2008) Malgorzata D. Gonciarz et al.   JOURNAL OF MOLECULAR BIOLOGY

Cryo-EM Structure of Dodecameric Vps4p and Its 2:1 Complex with Vta1p

(2008) Zhiheng Yu et al.   JOURNAL OF MOLECULAR BIOLOGY

Vacuolar Protein Sorting: Two Different Functional States of the AAA-ATPase Vps4p

(2008) Claudia Hartmann et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural Basis for Autoinhibition of ESCRT-III CHMP3

(2008) Suman Lata et al.   JOURNAL OF MOLECULAR BIOLOGY

Diverse Pore Loops of the AAA+ ClpX Machine Mediate Unassisted and Adaptor-Dependent Recognition of ssrA-Tagged Substrates

(2008) Andreas Martin et al.   MOLECULAR CELL

Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin

(2008) Antonina Roll-Mecak et al.   NATURE

Protein unfolding by a AAA+ protease is dependent on ATP-hydrolysis rates and substrate energy landscapes

(2008) Andreas Martin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Helical Structures of ESCRT-III Are Disassembled by VPS4

(2008) S. Lata et al.   SCIENCE

Structure and Disassembly of Filaments Formed by the ESCRT-III Subunit Vps24

(2008) Sara Ghazi-Tabatabai et al.   STRUCTURE