The heparin-binding growth factor midkine: the biological activities and candidate receptors

Accelerated Axonal Loss Following Acute CNS Demyelination in Mice Lacking Protein Tyrosine Phosphatase Receptor Type Z

(2012) Jeffrey K. Huang et al.   AMERICAN JOURNAL OF PATHOLOGY

Midkine Promotes Neuroblastoma through Notch2 Signaling

(2012) S. Kishida et al.   CANCER RESEARCH

Midkine Inhibits Inducible Regulatory T Cell Differentiation by Suppressing the Development of Tolerogenic Dendritic Cells

(2012) Y. Sonobe et al.   JOURNAL OF IMMUNOLOGY

Midkine in the pathology of cancer, neural disease, and inflammation

(2012) Kazuma Sakamoto et al.   PATHOLOGY INTERNATIONAL

ALKoma: A Cancer Subtype with a Shared Target

(2012) Hiroyuki Mano   Cancer Discovery

Notch Signaling Activated by Replication Stress-Induced Expression of Midkine Drives Epithelial-Mesenchymal Transition and Chemoresistance in Pancreatic Cancer

(2011) C. Gungor et al.   CANCER RESEARCH

Midkine induces epithelial-mesenchymal transition through Notch2/Jak2-Stat3 signaling in human keratinocytes

(2011) Yiping Huang et al.   CELL CYCLE

Stimulation of the midkine/ALK axis renders glioma cells resistant to cannabinoid antitumoral action

(2011) M Lorente et al.   CELL DEATH AND DIFFERENTIATION

Midkine and Alk signaling in sympathetic neuron proliferation and neuroblastoma predisposition

(2011) T. Reiff et al.   DEVELOPMENT

Premature Ligand-Receptor Interaction during Biosynthesis Limits the Production of Growth Factor Midkine and Its Receptor LDL Receptor-related Protein 1

(2011) Kazuma Sakamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Consensus Substrate Sequence for Protein-tyrosine Phosphatase Receptor Type Z

(2011) Akihiro Fujikawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Midkine prevented hypoxic injury of mouse embryonic stem cells through activation of Akt and HIF-1α via low-density lipoprotein receptor-related protein-1

(2011) Sang Hun Lee et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The Cytokine Midkine and Its Receptor RPTP  Regulate B Cell Survival in a Pathway Induced by CD74

(2011) S. Cohen et al.   JOURNAL OF IMMUNOLOGY

Midkine regulates amphetamine-induced astrocytosis in striatum but has no effects on amphetamine-induced striatal dopaminergic denervation and addictive effects: functional differences between pleiotrophin and midkine

(2011) E. Gramage et al.   NEUROSCIENCE

A Single Intracoronary Injection of Midkine Reduces Ischemia/Reperfusion Injury in Swine Hearts: A Novel Therapeutic Approach for Acute Coronary Syndrome

(2011) Hisaaki Ishiguro et al.   Frontiers in Physiology

The neurotrophic factor pleiotrophin modulates amphetamine-seeking behaviour and amphetamine-induced neurotoxic effects: evidence from pleiotrophin knockout mice

(2010) Esther Gramage et al.   ADDICTION BIOLOGY

Midkine-deficiency increases the anabolic response of cortical bone to mechanical loading

(2010) Astrid Liedert et al.   BONE

Plasma midkine level is a prognostic factor for human neuroblastoma

(2010) Shinya Ikematsu et al.   CANCER SCIENCE

Midkine Regulation of the Renin-Angiotensin System

(2010) Kenji Kadomatsu   CURRENT HYPERTENSION REPORTS

Increased trabecular bone formation in mice lacking the growth factor midkine

(2010) Claudia Neunaber et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Midkine, a heparin-binding cytokine with multiple roles in development, repair and diseases

(2010) Takashi MURAMATSU   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Osteocyte-derived HB-GAM (pleiotrophin) is associated with bone formation and mechanical loading

(2009) S. Imai et al.   BONE

Midkine gene transfer after myocardial infarction in rats prevents remodelling and ameliorates cardiac dysfunction

(2009) Arihiro Sumida et al.   CARDIOVASCULAR RESEARCH

Integrin ανβ3 is a pleiotrophin receptor required for pleiotrophin-induced endothelial cell migration through receptor protein tyrosine phosphatase β/ζ

(2009) Constantinos Mikelis et al.   FASEB JOURNAL

Circulating midkine in Crohnʼs disease: Clinical implications

(2009) Malgorzata Krzystek-Korpacka et al.   INFLAMMATORY BOWEL DISEASES

The growth factor midkine regulates the renin-angiotensin system in mice

(2009) Akinori Hobo et al.   JOURNAL OF CLINICAL INVESTIGATION

Cellular expression ofMidkine-aandMidkine-bduring retinal development and photoreceptor regeneration in zebrafish

(2009) Anda-Alexandra Calinescu et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Kidney calling lung and call back: how organs talk to each other

(2009) J. Floege et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Receptor Type Protein Tyrosine Phosphatase  -Pleiotrophin Signaling Controls Endocytic Trafficking of DNER That Regulates Neuritogenesis

(2008) N. Fukazawa et al.   MOLECULAR AND CELLULAR BIOLOGY

Inhibition of midkine alleviates experimental autoimmune encephalomyelitis through the expansion of regulatory T cell population

(2008) J. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA