Article
Plant Sciences
Swetha Sudha Nagamalla, Malini Devi Alaparthi, Sunitha Mellacheruvu, Ravindar Gundeti, Jana Priya Sony Earrawandla, Someswar Rao Sagurthi
Summary: The study investigated the impact of drought stress on two cotton varieties, revealing that Bt cotton showed stronger drought tolerance compared to non-Bt cotton at the protein expression and physiological levels. This finding may aid in breeding new drought-tolerant and high-yielding cotton hybrid varieties.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Environmental Sciences
Ng. Kunjarani Chanu, Madan Kumar Mandal, Akanksha Srivastava, Neha Chaurasia
Summary: The study investigated the effects of pyrethroid insecticide alpha-cypermethrin on cyanobacteria Anabaena sp. NC-K1, revealing upregulation of various proteins involved in stress responses, photosynthesis, translation, and DNA repair. This proteomic modulation allowed Anabaena sp. NC-K1 to maintain cellular metabolism and homeostasis against pesticide stress.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Chemistry, Analytical
Guangyao Wu, Hongchao Geng, Rongfang Xu, Min Deng, Changcheng Yang, Chengfeng Xun, Ying Wang, Qingyun Cai, Ping Chen
Summary: In this study, a CaTiO3/Al3+/Pr3+/Sm3+ nanocomposite was developed for efficient separation of exosomes and applied to serum samples from Alzheimer's disease patients. Through 2-DE separation and MALDI TOF/TOF mass spectrometry analysis, proteins related to the pathogenesis of AD were identified in the exosomes.
Article
Environmental Sciences
Gyanendra Kumar Rai, Abida Parveen, Gayatri Jamwal, Umer Basu, Ranjeet Ranjan Kumar, Pradeep K. Rai, Jag Paul Sharma, Adel Alalawy, Mohammed A. Al-Duais, Mohammad Anwar Hossain, Muhammad Habib Ur Rahman, Ali Raza, Subhan Danish, Mohamed Sakran
Summary: Advances in proteome research have allowed for a deeper understanding of metabolic pathways and mechanisms related to abiotic stress tolerance. This study examined the antioxidant capacity of four tomato genotypes under drought stress and identified differentially expressed proteins in two selected genotypes. The findings may contribute to enhancing drought tolerance in tomato cultivars and building a comprehensive proteome database for improving crop resilience in drought-stress conditions.
Review
Biochemistry & Molecular Biology
Reza Ranjbar, Amir Ebrahimi, Amirhossein Sahebkar
Summary: Helicobacter pylori infection is a common health problem with various diagnostic methods available. Non-invasive methods such as urea breath test are preferred, while molecular methods like PCR-based methods and next-generation sequencing have shown good sensitivity and specificity. Point of care devices and biosensors, particularly aptasensors, play an important role in H. pylori diagnosis due to their speed, accuracy, and ease of handling. Emerging techniques like MALDI-TOF MS are considered fast and accurate for identifying and differentiating H. pylori species.
CURRENT PHARMACEUTICAL BIOTECHNOLOGY
(2023)
Article
Chemistry, Applied
Xue Yi Tan, Azizah Misran, Leona Daniela Jeffery Daim, Benjamin Yii Chung Lau
Summary: Four methods were evaluated to extract proteins from Musang King durian pulps, with acetone-phenol method producing the best results. Differential protein analyses revealed that 15 proteins were down-regulated and 3 proteins were up-regulated after a year of frozen storage. This study indicates that frozen storage affects protein expression in various functional aspects.
Article
Microbiology
Helena Berlamont, Chloe De Witte, Sofie De Bruyckere, James G. Fox, Steffen Backert, Annemieke Smet, Filip Boyen, Freddy Haesebrouck
Summary: The study identified 93 gastric Helicobacter isolates of 10 different species using MALDI-TOF MS to establish a more elaborate reference database. The in-house database correctly identified all isolates and resulted in 82% correct species identification based on the top two matches. A dendrogram was also constructed to show phylogenetic relationships among the species.
Article
Agriculture, Dairy & Animal Science
Conrado Carrascosa, Remigio Martinez, Esther Sanjuan, Rafael Millan, Cristobal del Rosario-Quintana, Felix Acosta, Alfredo Garcia, Jose R. Jaber
Summary: New cases of blue cheese discoloration have prompted recent research to identify the causal agent and factors favoring blue pigment appearance. Testing on samples from a cheese farm confirmed tap water as the initial contaminated source, essential in preventing Pseudomonas contamination.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Biochemical Research Methods
Sangeeta Roy, Bodhisattwa Saha, Swati Gupta Bhattacharya
Summary: The study revealed the allergenic potency of Aspergillus ochraceus and identified 10 IgE-binding proteins through an immunoproteomic approach. The major allergen NADP(+)-dependent glycerol dehydrogenase (GldB) was identified, along with other IgE-binding proteins with homology to known allergens. These findings provide valuable insights for developing hypoallergenic vaccines and specific immunotherapeutic techniques for fungal allergy.
JOURNAL OF PROTEOMICS
(2021)
Article
Multidisciplinary Sciences
Sharifah Zakiah Syed Sulaiman, Wei Miao Tan, Rozanaliza Radzi, Intan Nur Fatiha Shafie, Mokrish Ajat, Rozaihan Mansor, Suhaila Mohamed, Norasfaliza Rahmad, Angela Min Hwei Ng, Seng Fong Lau
Summary: This study compared the proteomic changes in the synovial fluid of surgically and chemically induced osteoarthritis (OA) models. The surgical model showed a wider range of protein changes, while the chemical model had slower OA progression.
Article
Biochemistry & Molecular Biology
Lara Aparecida Buffoni de Campos Carneiro, Joel Wurman, Paul Dupree, Richard John Ward
Summary: Trichoderma reesei produces a beta-galactosidase that can hydrolyze xyloglucan oligosaccharides from tamarind and jatoba seed storage xyloglucans. The study found that the enzyme has a preference for galactosylated oligosaccharides and non-reducing end dexylosylated oligosaccharides. The synergistic depolymerization of xyloglucan by TrBga1 and alpha-xylosidase reveals insights into plant cell wall structure and evolutionary mechanisms of debranching enzymes.
Article
Food Science & Technology
Xue Li, Xiaorong Deng, Xin Guo, Yabo Wei, Yunfeng Zhao, Xiaobing Guo, Xinrong Zhu, Jian Zhang, Ling Hu
Summary: The present study investigates the freshness indicator protein of Coregonus peled and the effects of oxidation on the quality of fish during 4 degrees C storage. A total of 382 differential proteins were identified, and 20 proteins related to oxidation were found to have the potential as biomarkers for protein oxidative damage. Actin was identified as an indicator for fish softening during postmortem storage. The changes in protein structure and biomarkers were influenced by oxidation. Bioinformatics analysis suggested that differentially expressed proteins participated in the metabolic pathway during 4 degrees C storage.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Ji Yeong Yang, Jong-Bae Kim, Pyeongjae Lee, Sa-Hyun Kim
Summary: Evodiamine inhibits the growth of H. pylori by downregulating gene expressions related to replication and transcription machineries of the bacteria. Moreover, evodiamine also suppresses urease expression, leading to reduced translocation of CagA and VacA proteins into AGS cells. Additionally, evodiamine inhibits the activation of signaling proteins induced by H. pylori infection, contributing to reduction of IL-8 production in AGS cells.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Microbiology
Eva Gato, Ignacio Pedro Constanso, Bruno Kotska Rodino-Janeiro, Paula Guijarro-Sanchez, Tyler Alioto, Manuel Jesus Arroyo, Gema Mendez, Luis Mancera, Marta Gut, Ivo Gut, Miguel Alvarez-Tejado, German Bou, Marina Oviano
Summary: Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) has been used for direct detection of KPC-producing isolates by analyzing the 11,109 Da mass peak representing the P019 protein. The study found the P019 peak prevalence in bla(KPC) K. pneumoniae isolates to be 49.2%, while it was absent in other carbapenemase or noncarbapenemase producers. Variability of P019 presence was observed in different geographical locations within the EuSCAPE collection, indicating a need for reconsideration when applying this technique in a clinical setting.
JOURNAL OF CLINICAL MICROBIOLOGY
(2021)
Article
Polymer Science
Hiroyuki Ohshima
Summary: This study develops a general theory for the time-dependent transient electrophoresis of a weakly charged spherical colloidal particle in a polymer gel medium. The Laplace transform of the transient electrophoretic mobility is derived by considering the hydrodynamic interaction between the particle and the gel medium based on the Brinkman-Debye-Bueche model. The theory covers both transient gel electrophoresis and transient free-solution electrophoresis, with the relaxation time for the former being shorter and decreasing as the Brinkman screening length decreases.
Letter
Dermatology
Wenxin Zhang, Xiangqian Li, Bofu Chen, Jianzhong Zhang, Cheng Zhou
INDIAN JOURNAL OF DERMATOLOGY VENEREOLOGY & LEPROLOGY
(2023)
Letter
Dermatology
Lingzhi Zhong, Houmin Li, Jianzhong Zhang
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2023)
Article
Optics
Zhongrui Han, Fengjun Tian, Yipeng Lu, Guanqu Hu, Youzhi Chen, Zhibin Zeng, Chao Liu, Xinghua Yang, Li Li, Jianzhong Zhang
Summary: A single-polarization hollow core anti-resonant fiber (HC-ARF) in the terahertz (THz) region is proposed, with excellent single-polarization behavior achieved through material parameter optimization. The introduction of epsilon-near-zero (ENZ) material into high resistance silicon tubes further improves the single polarization behavior, enlarging the polarization extinction ratio (PER) and greatly improving birefringence. Configuration parameter optimization is conducted to obtain high PER and birefringence at 1 THz. The proposed single-polarization HC-ARF has great potential applications in polarization sensitive communication and THz band sensors.
Article
Immunology
Qi Zhao, Yu-Meng Jing, Mao-Tao He, Li Jing, Yan-Feng Xi, Jian-Zhong Zhang
Summary: Lycium barbarum polysaccharides (LBP) can ameliorate cerebral ischemia/reperfusion injury exacerbated by hyperglycemia by protecting the blood-brain barrier. The study found that LBP pretreatment reversed the increase in neurological deficit, infarct volume, cell apoptosis, and IgG leakage associated with hyperglycemia. Furthermore, LBP therapy also reversed the detrimental effects on endothelium, astrocytes, tight junctions, and basement membrane integrity caused by hyperglycemia.
TRANSPLANT IMMUNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Yiran Li, Dong Zhao, Xueyi Ma, Jianzhong Zhang, Jian Zhao
Summary: This paper proposes a panoramic displacement field measurement method to accurately measure the shape and panoramic displacement field of objects with complex morphologies. The method is based on the robust subset-based DIC algorithm and Zhang's calibration method, and it reconstructs the 3D shape and estimates the full-field displacements of complex surfaces from multi-view stereo camera pairs. The proposed method also determines the scale factor of the 3D reconstructed surface and stitches multiple 3D reconstructed surfaces using laser point cloud data. The experimental results confirm the accuracy of the proposed method in measuring panoramic shape and full-field displacement of complex objects.
APPLIED SCIENCES-BASEL
(2023)
Article
Microbiology
Jie Gong, Xin-Fei Chen, Xin Fan, Juan Xu, Han Zhang, Ruo-Yu Li, Sharon C-A Chen, Fanrong Kong, Shu Zhang, Zi-Yong Sun, Mei Kang, Kang Liao, Da-Wen Guo, Zhe Wan, Zhi-Dong Hu, Yun-Zhuo Chu, Hong-Mei Zhao, Gui-Ling Zou, Chong Shen, Yuan-Yuan Geng, Wei-Wei Wu, He Wang, Fei Zhao, Xin Lu, Li-Hua He, Gui-Ming Liu, Ying-Chun Xu, Jian-Zhong Zhang, Meng Xiao
Summary: This study presents the population structure of 551 global C. albicans strains, with 370 strains' antifungal susceptibilities tested. The results show that 66.6% of the azole-nonsusceptible/non-wild-type strains belong to Clade 1. Within Clade 1, two nested subclades (Clade 1-R and Clade 1-R-alpha) exhibit higher azole resistance and are distributed in different cities in China. This study highlights the importance of monitoring the spread of these drug-resistant subclades for public health.
MICROBIOLOGY SPECTRUM
(2023)
Article
Oncology
Xiao Chen, Jianzhong Zhang, Xinhan Lei, Lei Yang, Wanwan Li, Lu Zheng, Shuai Zhang, Yihan Ding, Jianing Shi, Lei Zhang, Jia Li, Tong Tang, WenJun Jia
Summary: This study evaluated the importance of tumor microenvironment (TME) in breast cancer and identified CD1C as a crucial gene that may serve as a prognostic marker and a treatment target for breast cancer.
Article
Dermatology
Zirui Gao, Yuanqing Dou, Pei Zhao, Caroline J. Wang, Jianzhong Zhang
Summary: This retrospective cohort study evaluated the efficacy and safety of dupilumab in the treatment of prurigo nodularis in adults. The results showed that dupilumab was effective in reducing pruritus and improving the quality of life for patients with prurigo nodularis. It was also found to be safe, with minimal adverse events, making it a potential therapeutic option.
Article
Gastroenterology & Hepatology
Kangle Zhai, Yanan Gong, Lu Sun, Lihua He, Zhijing Xue, Yaming Yang, Mengyang Fang, Jianzhong Zhang
Summary: Using IgY for H. pylori detection is more advantageous than for treatment. DNA starvation/stationary phase protection protein was identified as an immunodominant antigen of H. pylori and may serve as a potential antigen target for the diagnosis of H. pylori infection.
Article
Engineering, Electrical & Electronic
Min Zhang, Zhihai Liu, Yu Zhang, Yaxun Zhang, Jianzhong Zhang, Xinghua Yang, Libo Yuan
Summary: This study proposes a method to use natural spider dragline silk (SDS) as a flexible light waveguide integrated into an optic device. By coupling the light propagating in a microfiber into the SDS, and then coupling it to another microfiber connected to a spectrometer, the output multimode interference spectrum can be changed based on the difference in the effective refractive index of the modes in the silk fiber. The presented interferometer proves that SDS is a natural independent light guide suitable for integrated optic devices.
JOURNAL OF LIGHTWAVE TECHNOLOGY
(2023)
Article
Microbiology
Yahui Guo, Xiaojie Yu, Jixiao Wang, De Hua, Yuanhai You, Qingbo Wu, Qinglong Ji, Jianzhong Zhang, Liefei Li, Yuan Hu, Zhonghui Wu, Xiaoyue Wei, Lianqun Jin, Fanliang Meng, Yuhua Yang, Xiaofeng Hu, Lijin Long, Songnian Hu, Heyuan Qi, Juncai Ma, Wenwen Bei, Xiaomei Yan, Haibin Wang, Zilong He
Summary: ST7 Staphylococcus aureus, which is highly prevalent in humans, pigs, and food in China, has rarely been reported to cause staphylococcal food poisoning (SFP). However, a recent outbreak of SFP caused by ST7 S. aureus strains occurred in two kindergartens in Hainan Province, China. Whole-genome sequencing analysis revealed the genetic characteristics and phylogenetic relationships of these SFP strains and provided insights into the potential risk of this emergent ST7 clone for SFP.
FRONTIERS IN MICROBIOLOGY
(2023)
Review
Dermatology
Yujing Zhang, Jianzhong Zhang, Cheng Zhou
Summary: Perinevoid alopecia (PA) is a rare type of alopecia areata (AA) that is associated with a pigmented nevus in the center. Two cases of PA were reported in this study, and a review of 14 cases from 11 previous studies was conducted. In one of the cases, PA was found to be combined with a halo nevus, and white terminal hairs were spared in the area of hair loss, which is rarely reported in the literature. It is suggested that antigens from melanocytes may be involved in the development of AA in PA.
CLINICAL COSMETIC AND INVESTIGATIONAL DERMATOLOGY
(2023)
Article
Microbiology
Hairui Wang, Yixin Gu, Lihua He, Lu Sun, Guilan Zhou, Xiaoli Chen, Xin Zhang, Zhujun Shao, Jianzhong Zhang, Maojun Zhang
Summary: Campylobacter is a main cause of gastroenteritis worldwide. A novel bacterial strain called Campylobacter gastrosuis sp. nov. was isolated from the gastric mucous of pigs in China in 2022.
Article
Oncology
Jiayi Zang, Ming Cui, Lin Xiao, Jianzhong Zhang, Rongrong Jing
Summary: In this study, the higher expression of FSP1 and CISD1 in gastric cancer tissues was associated with poor prognosis and potential immunotherapeutic targets. They were found to promote malignant tumor progression and inhibit ferroptosis in gastric cancer.
CLINICAL & TRANSLATIONAL ONCOLOGY
(2023)
Article
Oncology
Wen Xu, Yijun Le, Jianzhong Zhang
Summary: We created a diagnostic model to predict the survival rate of sebaceous gland carcinoma patients based on clinical and pathological prognostic risk factors. The model accurately predicts the 3-, 5-, and 10-year overall survival rates of patients. This is important for identifying high-risk patients early, providing personalized treatment and follow-up, and improving the survival rate of sebaceous gland carcinoma patients.
FRONTIERS IN ONCOLOGY
(2023)