Charge Requirements of Lipid II Flippase Activity in Escherichia coli

A Burkholderia cenocepacia MurJ (MviN) homolog is essential for cell wall peptidoglycan synthesis and bacterial viability

(2014) Yasmine Fathy Mohamed et al.   GLYCOBIOLOGY

MurJ is the flippase of lipid-linked precursors for peptidoglycan biogenesis

(2014) L.-T. Sham et al.   SCIENCE

Structure-Function Analysis of MurJ Reveals a Solvent-Exposed Cavity Containing Residues Essential for Peptidoglycan Biogenesis in Escherichia coli

(2013) E. K. Butler et al.   JOURNAL OF BACTERIOLOGY

Charge Composition Features of Model Single-span Membrane Proteins That Determine Selection of YidC and SecYEG Translocase Pathways inEscherichia coli

(2013) Lu Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for the drug extrusion mechanism by a MATE multidrug transporter

(2013) Yoshiki Tanaka et al.   NATURE

Structural insights into H+-coupled multidrug extrusion by a MATE transporter

(2013) Min Lu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structures of a Na+-coupled, substrate-bound MATE multidrug transporter

(2013) M. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proton-Dependent Gating and Proton Uptake by Wzx Support O-Antigen-Subunit Antiport Across the Bacterial Inner Membrane

(2013) S. T. Islam et al.   mBio

Structural Perspective of Peptidoglycan Biosynthesis and Assembly

(2012) Andrew L. Lovering et al.   Annual Review of Biochemistry

Wzx flippase-mediated membrane translocation of sugar polymer precursors in bacteria

(2012) Salim T. Islam et al.   ENVIRONMENTAL MICROBIOLOGY

A cationic lumen in the Wzx flippase mediates anionic O-antigen subunit translocation in Pseudomonas aeruginosa PAO1

(2012) Salim T. Islam et al.   MOLECULAR MICROBIOLOGY

Crystal structure of Staphylococcus aureus transglycosylase in complex with a lipid II analog and elucidation of peptidoglycan synthesis mechanism

(2012) C.-Y. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

From the regulation of peptidoglycan synthesis to bacterial growth and morphology

(2011) Athanasios Typas et al.   NATURE REVIEWS MICROBIOLOGY

Arginine in Membranes: The Connection Between Molecular Dynamics Simulations and Translocon-Mediated Insertion Experiments

(2010) Eric V. Schow et al.   JOURNAL OF MEMBRANE BIOLOGY

Structure of a cation-bound multidrug and toxic compound extrusion transporter

(2010) Xiao He et al.   NATURE

I-TASSER: a unified platform for automated protein structure and function prediction

(2010) Ambrish Roy et al.   Nature Protocols

The Bacterial Cell Envelope

(2010) T. J. Silhavy et al.   Cold Spring Harbor Perspectives in Biology

Flipping Lipids: Why an’ What’s the Reason for?

(2009) Sumana Sanyal et al.   ACS Chemical Biology

Streptococcus pyogenes YtgP (Spy_0390) Complements Escherichia coli Strains Depleted of the Putative Peptidoglycan Flippase MurJ

(2009) N. Ruiz   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Chemical Genetic Identification of Peptidoglycan Inhibitors Potentiating Carbapenem Activity against Methicillin-Resistant Staphylococcus aureus

(2009) Joann Huber et al.   CHEMISTRY & BIOLOGY

Crystal structure of the membrane-bound bifunctional transglycosylase PBP1b from Escherichia coli

(2009) M.-T. Sung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multidrug efflux transporters in the MATE family

(2008) Teruo Kuroda et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Involvement of an Essential Gene, mviN, in Murein Synthesis in Escherichia coli

(2008) A. Inoue et al.   JOURNAL OF BACTERIOLOGY

Importance of the Conserved Residues in the Peptidoglycan Glycosyltransferase Module of the Class A Penicillin-binding Protein 1b ofEscherichia coli

(2008) Mohammed Terrak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bioinformatics identification of MurJ (MviN) as the peptidoglycan lipid II flippase in Escherichia coli

(2008) N. Ruiz   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli

(2008) N. Ruiz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Murein (peptidoglycan) structure, architecture and biosynthesis in Escherichia coli

(2007) Waldemar Vollmer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES