Article
Medicine, General & Internal
Fuat H. Saner, Alexandra Frey, Bjoern-Ole Stueben, Dieter P. Hoyer, Katharina Willuweit, Martina Daniel, Jassin Rashidi-Alavieh, Jurgen W. Treckmann, Hartmut H. Schmidt
Summary: In this retrospective study of 82 patients who underwent liver transplantation for primary sclerosing cholangitis (PSC), the authors assessed morbidity, survival rates, PSC recurrence, and the impact of donor characteristics in long-term follow-up. The study showed that PSC patients had excellent 10-year survival rates and a lower lab-MELD score was associated with longer survival. Donor characteristics did not affect patient survival.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Transplantation
Steven Law, Oliver Cohen, Helen J. Lachmann, Tamer Rezk, Janet A. Gilbertson, Dorota Rowczenio, Ashutosh D. Wechalekar, Philip N. Hawkins, Reza Motallebzadeh, Julian D. Gillmore
Summary: The study found that outcomes of renal transplantation in patients with AA and AL amyloidosis were comparable to those with diabetic nephropathy, but poorer than patients with ADPKD. In AL amyloidosis, factors such as interventricular septum thickness and achievement of deep hematologic response pre-transplant significantly impacted patient survival.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2021)
Article
Medicine, General & Internal
Kalliopi Vallianou, Smaragdi Marinaki, Chrysanthi Skalioti, Sophia Lionaki, Maria Darema, Christina Melexopoulou, Ioannis Boletis
Summary: This study found that recurrence of Focal Segmental Glomerulosclerosis (FSGS) after kidney transplantation is relatively common, and timely diagnosis and treatment with plasmapheresis can induce remission in the majority of patients.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Christiaan M. C. Serbanescu-Kele Apor De Zalan, Simeon J. S. Ruiter, Aad P. van den Berg, Jan Pieter Pennings, Koert P. de Jong
Summary: Thermal ablation (TA) has been proven to be an effective and repeatable therapy for both primary and recurrent HCC, with the majority of recurrences being treatable with curative intent. Some patients can achieve good outcomes with TA alone without the need for orthotopic liver transplantation (OLTx).
EUROPEAN RADIOLOGY
(2022)
Article
Nutrition & Dietetics
Kao-Ming Hsu, Pei-Ru Lin, Ping-Fang Chiu, Yao-Peng Hsieh
Summary: This study investigated the subsequent renal function change following incident infectious diseases in living-donor liver transplant recipients. The results showed that hospitalization with major infections or pneumonia increased the risk of eGFR decline and adverse renal outcomes in these patients.
Article
Peripheral Vascular Disease
Ryo Nakamaru, Koichi Yamamoto, Hiroshi Akasaka, Hiromi Rakugi, Isao Kurihara, Takashi Yoneda, Takamasa Ichijo, Takuyuki Katabami, Mika Tsuiki, Norio Wada, Tetsuya Yamada, Hiroki Kobayashi, Kouichi Tamura, Yoshihiro Ogawa, Junji Kawashima, Nobuya Inagaki, Megumi Fujita, Kenji Oki, Kohei Kamemura, Akiyo Tanabe, Mitsuhide Naruse
Summary: The study found that female patients with bilateral primary aldosteronism have worse renal outcomes compared to male patients after receiving mineralocorticoid receptor antagonist treatment. Despite similar systolic blood pressure levels between the sexes, women experienced a greater decline in estimated glomerular filtration rate, especially during the late phase of 6 to 60 months post-treatment initiation.
Article
Medicine, General & Internal
Junseok Jeon, Hyejeong Park, Youngha Kim, Danbee Kang, Jung Eun Lee, Wooseong Huh, Eliseo Guallar, Juhee Cho, Hye Ryoun Jang
Summary: Renal dysfunction after heart transplantation is associated with poor survival. Perioperative RRT, use of inotropes/vasopressors, and non-use of ACEi/ARB were predictors of ESKD, emphasizing the need for an active renoprotective strategy during the perioperative period.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Multidisciplinary Sciences
Sophia Lionaki, Ilias Makropoulos, Konstantinos Panagiotellis, George Vlachopanos, Ioannis Gavalas, Smaragdi Marinaki, George Liapis, Ioannis Michelakis, Ioannis Bokos, Ioannis Boletis
Summary: Kidney transplant recipients with IgA nephropathy as the primary disease showed similar long-term outcomes compared to recipients with other causes of end-stage kidney disease. Recurrence of IgA nephropathy in the graft was significantly lower than focal segmental glomerulosclerosis recurrence, but higher than lupus nephritis or pauci-immune glomerulonephritis recurrence. Tacrolimus maintenance therapy was associated with lower rates of IgA nephropathy recurrence in the graft compared to cyclosporine.
Article
Surgery
Lynn D. Cornell, Hatem Amer, Jason K. Viehman, Ramila A. Mehta, John C. Lieske, Elizabeth C. Lorenz, Julie K. Heimbach, Mark D. Stegall, Dawn S. Milliner
Summary: Primary hyperoxaluria can lead to recurrent calcium oxalate deposits in kidney transplants, with higher levels of plasma and urine oxalate associated with increased risk of recurrence. Avoiding high plasma oxalate and reducing CaOx crystallization may help decrease the risk of recurrent oxalate nephropathy in patients with PH following kidney transplantation.
AMERICAN JOURNAL OF TRANSPLANTATION
(2022)
Review
Oncology
Muhammad Majdoub, Takafumi Yanagisawa, Fahad Quhal, Ekaterina Laukhtina, Markus von Deimling, Tatsushi Kawada, Pawel Rajwa, Alberto Bianchi, Maximilian Pallauf, Hadi Mostafaei, Marcin Chlosta, Benjamin Pradere, Pierre I. Karakiewicz, Manuela Schmidinger, Ronen Rub, Shahrokh F. Shariat
Summary: This meta-analysis summarizes research findings on the correlation between clinicopathological characteristics and post-surgery survival outcomes in non-metastatic renal cell carcinoma (RCC) patients. Several clinicopathological characteristics were associated with poor survival outcomes, while no features were predictive for late recurrence.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Article
Surgery
Masateru Yamamoto, Tsuyoshi Kobayashi, Naruhiko Honmyo, Akihiko Oshita, Tomoyuki Abe, Toshihiko Kohashi, Takashi Onoe, Saburo Fukuda, Ichiro Omori, Yasuhiro Imaoka, Hideki Ohdan
Summary: Patients with hepatocellular carcinoma beyond the Barcelona Clinic Liver Cancer criteria can benefit from liver resection based on a predictive formula that considers a high a-fetoprotein level, macrovascular invasion, and high total tumor burden. Risk stratification using these factors can predict the prognosis and guide treatment decisions.
Review
Urology & Nephrology
Dominic M. Taylor, Ailish M. Nimmo, Fergus J. Caskey, Rachel Johnson, Maria Pippias, G. J. Melendez-Torres
Summary: Chronic kidney disease (CKD) affects 850 million people worldwide, but existing evidence-based treatments are underutilized and there is inequity in access to care. This study identified that interventions with automated detection, educational support, and specialist review can improve CKD care, but patient perspectives were lacking in available literature.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2023)
Article
Biochemistry & Molecular Biology
Roberto Gramignoli, Aarati R. Ranade, Raman Venkataramanan, Stephen C. Strom
Summary: Pro-inflammatory cytokines can affect liver cell functions, particularly ammonia and drug metabolism, but do not necessarily indicate rejection or loss of cell graft.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Multidisciplinary Sciences
Ka Eun Kim, Dong Hyun Sinn, Moon Seok Choi, Honsoul Kim
Summary: HCC often recurs within a short period of time in patients who achieve a complete response to treatment with increased tumor marker levels, even if gadoxetic acid-enhanced MRI is negative. Short-term follow-up, including gadoxetic acid-enhanced MRI and systemic evaluation, is recommended.
Article
Microbiology
Gintare Vaitkute, Gordana Panic, Dagmar G. Alber, Intan Faizura-Yeop, Elaine Cloutman-Green, Jonathan Swann, Paul Veys, Joseph F. Standing, Nigel Klein, Mona Bajaj-Elliott
Summary: This study investigates the longitudinal dynamics of the gut microbiota and metabolome in paediatric haematopoietic stem cell transplantation, and reveals associations between them and clinical outcomes.
Article
Transplantation
Sandra Berody, Laurence Heidet, Olivier Gribouval, Jerome Harambat, Patrick Niaudet, Veronique Baudouin, Justine Bacchetta, Bernard Boudaillez, Maud Dehennault, Loic de Parscau, Olivier Dunand, Hugues Flodrops, Marc Fila, Arnaud Garnier, Ferielle Louillet, Marie-Alice Macher, Adrien May, Elodie Merieau, Francoise Monceaux, Christine Pietrement, Caroline Rousset-Rouviere, Gwenaelle Roussey, Sophie Taque, Julie Tenenbaum, Tim Ulinski, Rachel Vieux, Ariane Zaloszyc, Vincent Moriniere, Remi Salomon, Olivia Boyer
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2019)
Article
Transplantation
Stephanie Dufek, Tuula Holtta, Agnes Trautmann, Elisa Ylinen, Harika Alpay, Gema Ariceta, Christoph Aufricht, Justine Bacchetta, Sevcan A. Bakkaloglu, Aysun Bayazit, Rumeysa Yasemin Cicek, Ismail Dursun, Ali Duzova, Mesiha Ekim, Daniela Iancu, Augustina Jankauskiene, Guenter Klaus, Fabio Paglialonga, Andrea Pasini, Nikoleta Printza, Valerie Said Conti, Maria do Sameiro Faria, Claus Peter Schmitt, Constantinos J. Stefanidis, Enrico Verrina, Enrico Vidal, Karel Vondrak, Hazel Webb, Argyroula Zampetoglou, Detlef Bockenhauer, Alberto Edefonti, Rukshana Shroff
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2019)
Article
Endocrinology & Metabolism
Anya Rothenbuhler, Nathalie Fadel, Yahya Debza, Justine Bacchetta, Mamadou Tidiane Diallo, Catherine Adamsbaum, Agnes Linglart, Federico Di Rocco
JOURNAL OF BONE AND MINERAL RESEARCH
(2019)
Review
Endocrinology & Metabolism
Justine Bacchetta, Claire Bardet, Dominique Prie
METABOLISM-CLINICAL AND EXPERIMENTAL
(2020)
Article
Pediatrics
Stephanie Dufek, Elisa Ylinen, Agnes Trautmann, Harika Alpay, Gema Ariceta, Christoph Aufricht, Justine Bacchetta, Sevcan Bakkaloglu, Aysun Bayazit, Salim Caliskan, Maria do Sameiro Faria, Ismail Dursun, Mesiha Ekim, Augustina Jankauskiene, Guenter Klaus, Fabio Paglialonga, Andrea Pasini, Nikoleta Printza, Valerie Said Conti, Claus Peter Schmitt, Constantinos Stefanidis, Enrico Verrina, Enrico Vidal, Hazel Webb, Argyroula Zampetoglou, Alberto Edefonti, Tuula Holtta, Rukshana Shroff
PEDIATRIC NEPHROLOGY
(2019)
Review
Pediatrics
Pierre Cochat, Olivia Febvey, Justine Bacchetta, Etienne Berard, Natalia Cabrera, Laurence Dubourg
PEDIATRIC NEPHROLOGY
(2019)
Article
Pediatrics
Alexandra Bruel, Justine Bacchetta, Tiphanie Ginhoux, Christelle Rodier-Bonifas, Anne-Laure Sellier-Leclerc, Berengere Fromy, Pierre Cochat, Dominique Sigaudo-Roussel, Laurence Dubourg
PEDIATRIC NEPHROLOGY
(2019)
Article
Urology & Nephrology
Aurelia Berthlet-Thomas, Nathalie Tram, Laurence Dubourg, Sandrine Lemoine, Arnaud Molin, Justine Bacchetta
AMERICAN JOURNAL OF KIDNEY DISEASES
(2019)
Article
Urology & Nephrology
Dieter Haffner, Francesco Emma, Deborah M. Eastwood, Martin Biosse Duplan, Justine Bacchetta, Dirk Schnabel, Philippe Wicart, Detlef Bockenhauer, Fernando Santos, Elena Levtchenko, Pol Harvengt, Martha Kirchhoff, Federico Di Rocco, Catherine Chaussain, Maria Louisa Brandi, Lars Savendahl, Karine Briot, Peter Kamenicky, Lars Rejnmark, Agnes Linglart
NATURE REVIEWS NEPHROLOGY
(2019)
Article
Pediatrics
Mathilde Mauras, Justine Bacchetta, Anita Duncan, Marie-Pierre Lavocat, Barbara Rohmer, Etienne Javouhey, Sophie Collardeau-Frachon, Anne-Laure Sellier-Leclerc
PEDIATRIC NEPHROLOGY
(2019)
Article
Pediatrics
Justine Bacchetta, Tiphanie Ginhoux, Delphine Bernoux, Laurence Dubourg, Bruno Ranchin, Christelle Roger
Article
Endocrinology & Metabolism
Katharina Hohenfellner, Frank Rauch, Gema Ariceta, Atif Awan, Justine Bacchetta, Carsten Bergmann, Susanne Bechtold, Noelle Cassidy, Geroges Deschenes, Ewa Elenberg, William A. Gahl, Oliver Greil, Erik Harms, Nadine Herzig, Bernd Hoppe, Christian Koeppl, Malcolm A. Lewis, Elena Levtchenko, Galina Nesterova, Fernando Santos, Karl P. Schlingmann, Aude Servais, Neveen A. Soliman, Guenther Steidle, Clodagh Sweeney, Ulrike Treikauskas, Rezan Topaloglu, Alexey Tsygin, Koenraad Veys, Rodo von Vigier, Jozef Zustin, Dieter Haffner
JOURNAL OF INHERITED METABOLIC DISEASE
(2019)
Article
Transplantation
Justine Bacchetta, Claus Peter Schmitt, Gema Ariceta, Sevcan A. Bakkaloglu, Jaap Groothoff, Mandy Wan, Marc Vervloet, Rukshana Shroff, Dieter Haffner
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2020)
Article
Multidisciplinary Sciences
Christelle Arrondel, Sophia Missoury, Rozemarijn Snoek, Julie Patat, Giulia Menara, Bruno Collinet, Dominique Liger, Dominique Durand, Olivier Gribouval, Olivia Boyer, Laurine Buscara, Gaelle Martin, Eduardo Machuca, Fabien Nevo, Ewen Lescop, Daniela A. Braun, Anne-Claire Boschat, Sylvia Sanquer, Ida Chiara Guerrera, Patrick Revy, Mlanie Parisot, Ccile Masson, Nathalie Boddaert, Marina Charbit, Stphane Decramer, Robert Novo, Marie-Alice Macher, Bruno Ranchin, Justine Bacchetta, Audrey Laurent, Sophie Collardeau-Frachon, Albertien M. van Eerde, Friedhelm Hildebrandt, Daniella Magen, Corinne Antignac, Herman van Tilbeurgh, Geraldine Mollet
NATURE COMMUNICATIONS
(2019)
Article
Biochemistry & Molecular Biology
Ariane Zaloszyc, Philippe Choquet, Amira Sayeh, Maria Bartosova, Betti Schaefer, Ulrike Huegel, Gaelle Aubertin-Kirch, Christopher Healy, Francois Severac, Sebastien Rizzo, Georges Boivin, Franz Schaefer, Michel Fischbach, Justine Bacchetta, Seiamak Bahram, Claus Peter Schmitt
Summary: Chronic kidney disease often leads to bone disorders and cardiovascular mortality, and the G alpha(q/11)/PKC pathway in osteoblasts plays an important role in CKD-MBD.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)